Computer-Facilitated HPLC Method Development Using DryLab Software

Computer-Facilitated HPLC Method Development Using DryLab Software 

Software for computer-facilitated H PLC method development has been commercially available for the past two decades. The present chapter describes one such computer program DryLab (Rheodyne LLC, Rohnert Park, CA, USA). The detailed operation of this software is presented here, with a half dozen examples of its real-world application. The present version of DryLab is the result of two decades of continuing development and use by practicing chromatographers. 

HPLC method development can be carried out in a variety of ways [1]. Systematic, trial-and-error changes in conditions are generally used to achieve adequate resolution of the sample, with a common goal of baseline resolution (R 1.5) 

HPLC Made to Measure A Practical Handbook for Optimization. Edited by Stavros Kromidas Copyright 2006 WILEY-VCH Verlag GmbH Co. KGaA, Weinheim ISBN 3-527-31377-X 

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Snyder, L.R. and Wrisley, L. (2006) Computer-Facilitated HPLC Method Development Using DryLab Software, in HPLC Made to Measure, (Ed. S.Kromidas), Wiley-VCH, Weinheim. 

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