Compounding trends

Merour J. Y., Piroelle S., Joseph B. Synthesis and Reactivity of lH-Indol-3(2H)-One and Related Compounds Trends Heterocycl. Chem. 1997 J 115-126 Keywords inverse electron-demand Diels-Alder reaction, indolone... 

Balakin, K., Savchuk, N., Tetko, I. In silica approaches to prediction of aqueous and DM SO solubility of drug-like compounds trends, problems and solutions. Curr. Med. Chem. 2006, 13, 223-241. 

OUiaro P, Haynes RK, Meunier B, Yuthavong Y. (2001) Possible modes of action of the artemisinin-type compounds. Trends Parasitol 17 122-126. 

When considering Pv compounds, trends are not so clear as any change is accompanied by a complete rehybridisation of phosphorus, especially in phosphorylated series. Nevertheless, additivity rules are approximately obeyed in compounds of type XYP(Z)F,<1969,e9) for... 

Rice-Evans, C.A., Miller, N.J., and Paganga, G., Antioxidant properties of phenolic compounds, Trends Plant Set, 2, 152, 1997. 

Redox potential data frequently correlate with parameters obtained by other spectroscopic measurements. The correlation of E° potentials with gas-phase ionization potentials has already been briefly discussed. Electronic transitions observed by UV-visible spectroscopy involve the promotion of an electron from one orbital to another and this can be viewed as an intramolecular redox reaction. If the promotion involves the displacement of an electron from the HOMO to the LUMO, then the redox potentials for the reduction of the compound, °REd, and for its oxidation, °ox, are of importance. For a closely related series of compounds, trends in oxidation and reduction potentials can be related to shifts in the absorption frequency, v. If the structural perturbation causes the HOMO and the LUMO to rise or fall in energy in tandem, then (E°RED — E°ox) will remain constant in such cases the HOMO—LUMO frequency (energy) will be essentially independent of the structural perturbation. Where there is a differential influence of the perturbation on the HOMO and the LUMO, then ( °red E°ox) will vary as will the energy of the electronic transition. In such cases a linear correlation of °red or E°0x may result. In the limit the energy of the HOMO, or more usually the LUMO, will be unaffected by structural perturbation where the acceptor orbital is pinned, direct linear correlation of E°Gx with v should be apparent. With E°ox and v in a common energy unit, the plot E°0x versus v should have a slope close to one.33-36... 

Lin, Y. Smart, N.G. Wai, C.M. Supercritical fluid extraction and chromatography of metal chelates and organometallic compounds, Trends Anal. Chem. 14 (1995) 123-133. 

Barcelo, D. 1991. Applications of gas chromatographymass spectrometry in monitoring environmentally important compounds. Trends Anal. Chem. 10 323-329. 

Dewulf, J., H. Van Langenhove, and T. Huybrechts. 2006. Developments in the analysis of volatile halogenated compounds. Trends Anal. Chem. 25 300-309. 

Rubio, S. and D. Perez-Bendito. 2003. Supramolecular assemblies for extracting organic compounds. Trends Anal. Chem. 22 470-485. 

F. Adams, S. Slaet, Improving the reliability of speciation analysis of organometallic compounds, Trends Anal. Chem., 19 (2000), 80-85. 

Made], K. Microwave-assisted and cloud point extraction in determination of drugs and other bioactive compounds. Trends Anal. Chem. 28, 436-446 (2009)... 

Irth, H. and Brinkman, U. A. Th. 1990. Ligand exchange for trace enrichment and selective detection of ionic compounds. Trends Anal. Chem., 9 235-241. 

Moore, D.E. (1987) Techniques for analysis of photodegradation pathways of medicinal compounds, Trends Anal. Chem., 6, 234—238. 

Luque de Castro, M. D. and Tena, M. T., Strategies for supercritical fluid extraction of polar and ionic compounds, Trends Anal. Chem., 15, 32-31, 1996. 

But, biomolecules are not rigid spheres they have different shapes that prodnce different collision cross sections d. To a first approximation, when d is plotted as a function of m, unique mobility-to-mass correlation curves (often called trend lines) are generated for different classes of compounds. Trend lines were first observed by... 

Pawliszyn, J. (1995). New directions in sample preparation for analysis of organic compounds. Trends in Analytical Chemistry, Vol. 14, No. 3, pp. 113-122... 

Pereira A and Radler de Aquino Neto F (1999) High temperature high-resolution gas chromatography Breaching the barrier to the analysis of polar and high molecular weight compounds. Trends in Analytical Chemistry 18 126-136. 

Abstract The activation of C-H bonds by oxidative addition in about 30 different substrates has been examined with three closely related metal species, [Tp RhL], where L = CNneopentyl, PMes, and P(OMe)3. Kinetic studies of the reductive elimination of R-H provided data to ascertain the relative metal-carbon bond strengths for a wide range of compounds. Trends in these bond strengths reveal that there are two classes of C-H substrates parent hydrocarbons and substituted methanes. DPT calculations are used to support the observed trends, and some generalizations are made by comparison to other metal systems. 

Yuan JS, Himanen SJ, Holopainen JK, Chen F, Stewart CN Jr (2009) Smelling global climate change mitigation of function for plant volatile organic compounds. Trends Ecol Evol 24 323-331... 

G. Surpateanu, S. Fourmentin, D. Landy, G. G. Surpateanu and P. Decock, Cyclodextrin Derivatives Used in the Detection and the Remediation of Volatile Organic Compounds , Trends Heterocycl. Chem., 2006, 11, 63. 

R Bentley. The configuration of hiotin and related compounds. Trends Biochem Sd 11 51-56, 1985. 

Horaguchi, T., Synthesis of benzofurans using photocychsation reactions of aromatic carbonyl compounds. Trends Heterocyclic Chem., 6, 1-19, 1997. 

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