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Complementarity-determining regions CDRs

The differences in sequence within the variable region produce a practically unlimited number of possible three-dimensional arrangements for the amino acid side chains to form the complementarity-determining region (CDR), which actually binds to the antigen. [Pg.19]

Figure 22.25. Schematic illustration of an immunoglobulin IgG. The complex consists of two heavy (H) chains and two light (L) chains. Somatic hypermutation that greatly contributes to antibody diversity occurs in the variable (V) regions of both the heavy and the light chins, especially the complementarity-determining regions (CDR). Figure 22.25. Schematic illustration of an immunoglobulin IgG. The complex consists of two heavy (H) chains and two light (L) chains. Somatic hypermutation that greatly contributes to antibody diversity occurs in the variable (V) regions of both the heavy and the light chins, especially the complementarity-determining regions (CDR).
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See also in sourсe #XX -- [ Pg.55 ]



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