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Comparative genomics application

Array-based comparative genomic hybridization (a-CGH) is a genomic analysis system that allows identification of alterations in DNA sequence and copy number, with a potential goal of individualized diagnosis and targeted cancer therapy.35,36 A number of reports have described application of a-CGH to DNA extracted from FFPE tissues, with variable results.35,37 38... [Pg.52]

Pinkel D, Albertson DG. Array comparative genomic hybridization and its applications in cancer. Nat... [Pg.296]

Chain. P., Kurtz, S., Ohlebusch, E., and Slezak, T. (2003) An applications-focused review of comparative genomics tools capabilities, limitations and future challenges. Brief. Bioinform. 4, 105-123. [Pg.73]

APPLICATION OF COMPARATIVE GENOMICS—RECONSTRUCTION OF METABOLIC PATHWAYS... [Pg.382]

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