Codeine Anticholinergics

Colitis may result from various gut infections, especially amoebic colitis. Clindamycin, vancon cin or metronidazole may be used in treatment. The diarrhoea of colitis states may be treated with normal ANTIDIARRHOEALS, e.g. the opioids codeine, morphine, diphenoxylate and loperamide. The colic may respond to ANTISPASMODICS, e.g. the anticholinergics atropine, hyoscine, dicyclomine, propantheline. Meheverine is a direct-acting antispasmodic effective in some types of gut colic. 

Herbert ME, Brewster GS (2000) Myth Codeine is an effective cough suppressant for upper respiratory tract infections. West J Med 173 283 Higenbottam TW (1987) Anticholinergics and cough. Postgrad Med J 63(Suppl l) 75-78... 

D. Glutethimide often produces mydriasis (dilated pupils) and other anticholinergic side effects, and patients may exhibit prolonged and cyclic or fluctuating coma. It is sometimes taken in combination with codeine ( loads ), which may produce opioid effects. 

Furthermore, the classification of anticholinergic drugs is at times suspect, since drugs such as cimetidine, codeine, digoxin, nifedipine, and even warfarin have been included in some assessments. Classification of anticholinergic actions of medications according to their effects on muscarinic receptors and measured anticholinergic effects in vivo would be helpful fll f. 

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