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Closure of the hard palate

C. Implantation to closure of the hard palate Adult female reproductive functions and development of Segment I Segment II Segment I Segment II Segment II Multigeneration One-generation developmental toxicity Developmental neurotoxicity... [Pg.260]

D = Closure of the hard palate to the end of pregnancy (fetal period)... [Pg.2]

The objectives of a teratology study (see Note 2) are to evaluate the effects of the test item on embryonic and fetal development when administered during the period of organogenesis, i.e., from uterine implantation to the closure of the hard palate (see Note 3)... [Pg.95]

Implantation of the embryo in the rat occurs around GD6 and closure of the hard palate around GD17. [Pg.108]

The dosing period, from day 11 through to at least day 35 post-coitum covers the stages of gestation from implantation to closure of the hard palate (the period of major organogenesis). [Pg.161]

Pregnancy is not diagnosed until GD 18-20. Thus, only a portion of the period between implantation and closure of the hard palate (close to GD 50 in the cynomolgus monkey) is... [Pg.198]

These studies are conducted in order to detect adverse effects on the pregnant female and the development of the embryo and fetus exposed in utero. Basically the period between implantation and closure of the hard palate is being investigated. In the NFIP, however, only the period between postimplantation... [Pg.386]

What is the maternal and embryofetal toxicity and teratogenic potential and toxicokinetics of a test article when administered daily to pregnant rats from implantation to closure of the hard palate ... [Pg.881]

The aim of this study, often called teratogenicity study , is to detect adverse effects of the test compound on the pregnant female and on the development of the embryo and fetus, from implantation of the blastocyte to closure of the hard palate. Adverse effects to be assessed are enhanced toxicity to the pregnant organism in relation to the non-pregnant, death of the embryo or fetus, altered growth and structural changes in the conceptus. [Pg.843]

See other pages where Closure of the hard palate is mentioned: [Pg.260]    [Pg.2]    [Pg.7]    [Pg.98]    [Pg.114]    [Pg.83]    [Pg.84]    [Pg.388]    [Pg.845]    [Pg.48]    [Pg.46]    [Pg.260]    [Pg.2]    [Pg.7]    [Pg.98]    [Pg.114]    [Pg.83]    [Pg.84]    [Pg.388]    [Pg.845]    [Pg.48]    [Pg.46]    [Pg.158]    [Pg.141]    [Pg.143]    [Pg.80]    [Pg.65]   
See also in sourсe #XX -- [ Pg.2 , Pg.7 , Pg.95 , Pg.98 , Pg.108 , Pg.114 , Pg.161 , Pg.198 ]



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