Climatic zones concept

Climatic Zones — The four zones in the world that are distinguished by their characteristic, prevalent annual climatic conditions. This is based on the concept described by W. Grimm (Drugs Made in Germany, 28 196-202, 1985 and 29 39-47, 1986). 

In subsequent years, a number of guidance documents related to stability of pharmaceutical products have been issued. The guidance documents are based on the concept of climatic zones (1). There are four zones based on Mean Kinetic Temperature and Mean Annual Relative Humidity (RH) Zone I (temperate climate), e.g., Canada and Northern European, Zone 11 (subtropical), e.g., the United States and Southern Europe, Zone III (hot and dry), e.g.. Egypt and Zone IV (hot and humid), e.g., Brazil. The United States, Europe, and Japan are all in Zones I and II so the ICH guidelines are applicable for these zones. 

Climatic Zones [ICH Q1A] — Concept of dividing the world into four zones based on defining the prevalent annual climatic conditions. 

Soil classification has been oriented to soil properties in recent years, but still is tempered with concepts of soil genesis, with external associations, and with the use of the soil. The first systematic classification was by Dokuchaiev in Russia in 1882, Based upon field and laboratory characteristics, soils were grouped into three categories—normal soils of the dry-land vegetative zones and moors, transitional soils of washed or dry land sediments and abnormal soils. The system involved properties of the soil with external associations of climate and vegetation. Later, an associate (Sibirtsev) renamed the highest classes zonal intrazonal, and azonal. 

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