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Classification of drug-release textiles

Drug-encapsulated non-woven fabrics are produced by putting small fibres together in the form of sheets or web-like stractures following entangling of drug-loaded fibres or filaments mechanically, thermally, or chemically. Non-woven fabrics can be produced to meet specific requirements and are used extensively as bacterial barriers, sterile [Pg.132]

The electrospinning process was established in 1934 when the first patent on electrospinning was filed (Formhals, 1934). Nanofibres based on polymeric materials can be produced featuring a wide range of dimensions. The diameter of the fibre can range from 10 up to several hundred nanometres. Electrospinning can be carried out [Pg.133]

Phase separation is another method that can be employed for the preparation of nanoscale sttucmres and is frequently used to prepare three-dimensional tissue-engineering scaffolds. Phase separation of a polymer solution can produce a polymer-rich domain and a solvent-rich domain and this morphology can be fixed by quenching under low temperamre conditions. [Pg.135]

Removal of the solvent through freeze-drying or extraction can produce porous polymer scaffolds. Phase separation can be induced by changing the temperature or by adding non-solvent to the polymer solution. These are known as thermally induced and non-solvent-induced phase separation, respectively. The scaffolds obtained by [Pg.135]


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