Classification According to the Electrolyte System

If both the analytes and the EOF move in the same direction, as with CIE, the system is classified as coelectroosmosis, and the analytes reach the detector faster than they would as a result of their own mobilities. If the analytes move in the opposite direction from the analytes, the system is classified as counterelectroosmosis, and the analytes reach the detector later than they would as a result of their own mobilities. If the EOF is suppressed by eliminating the effective charge on the capillary wall, then the analytes reach the detector solely as a result of their own mobility. The last approach is often taken for the analysis of large peptides and proteins, where ionic or hydrophobic interactions between the analyte and the capillary wall result in peak tailing or total adsorption. 

Capillary electrophoresis is similar to chromatography in many respects, and most of the words used in chromatography are also found in CE. For example, resolution and efficiency are common to both techniques and are defined in a similar way. However, some of the terminology is different, as illustrated in Table 4.1. For example, in chromatography, a column in used to separate the analytes in electrophoresis, a capillary is used. In chromatography a pump is used to propel the sample through the column in electrophoresis, there is no external pumping system, and the 

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