Citrulline phosphorylase

This enzyme [EC 2.1.3.3], also known as ornithine car-bamoyltransferase and citrulline phosphorylase, catalyzes the reaction of carbamoyl phosphate with L-orni-thine to produce L-citrulline and orthophosphate. 

ORNITHINE TRANSCARBAMOYLASE NITRIC OXIDE SYNTHASE Citrulline phosphorylase,... 

Citrullinase. The bacterial enzyme that degrades citrulline has been called citrullinase, citrulline ureidase and citrulline phosphorylase. The reaction requires inorganic phosphate, Mg++, and ADP, and ATP is formed together with NH3, CO2, and ornithine. Arsenate supports the breakdown of citrulline in the absence of phosphate and adenine nucleotides. The mechanism of the phosphorolysis was shown by Jones et to be straightforward the first products are ornithine and carbamyl phosphate, which had previously been considered to be too unstable to exist free. Carbamyl phosphate transfers its phosphate to ADP in a reversible kinase reaction, and the carbamyl group also can react with ornithine to form citrulline (VI). These reversible reactions explain the requirement for stoichiometric amounts of adenine nucleotides for a coupled reaction to remove the labile phosphate. Carbamic acid may equilibrate non-... 

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