Tramadol Citalopram

A 70-year-old woman, who had been taking citalopram 10 mg/day for 3 years for depression, began taking tramadol 50 mg/day) for pain relief and rapidly developed tremor, restlessness, fever, and confusion (121). 

The symptoms settled after tramadol was withdrawn. The same symptoms recurred 1 year later, when tramadol 20 mg/day was added to the citalopram. Genotyping for functional polym orphisms in... 

Mahlberg R, Kunz D, Sasse J, Kirchheiner J. Serotonin syndrome with tramadol and citalopram. Am J Psychiatry 2004 161 1129. 

Clinically important, potentially hazardous interactions with amitriptyline, amoxapine, amphetamines, bupropion, citalopram, clomipramine, cyproheptadine, desipramine, dextroamphetamine, dextromethorphan, diethylpropion, dopamine, doxepin, entacapone, ephedra, ephedrine, epinephrine, fluoxetine, fluvoxamine, ginseng, imipramine, levodopa, mazindol, meperidine, methamphetamine, nefazodone, nortriptyline, paroxetine, phendimetrazine, phentermine, phenylephrine, pizotifen, propoxyphene, protriptyline, pseudoephedrine, rizatriptan, sertraline, sibutramine, sumatriptan, sympathomimetics, tramadol, tricyclic antidepressants, trimipramine, tryptophan, venlafaxine, zolmitriptan... 

Ajmaline, alprenolol, amiflamine, amphetamine, aprindine, captopril, chlorpheniramine, cinnarizine, citalopram, clomipramine, clozapine, codeine, desipramine, dolasteron, encainide, flecainide, fluoxetine, fluphenazine, haloperidol, hydrocordone, imipramine, loratidine, methoxyphenamine, 3,4-methylenedioxymethamphetamine, metoprolol, mexiletine, (S)- and (i )-mianserin, nifedipine, olanzapine, omeprazole, oxycodone, perhexiline, phenformin, propaphenone, propranolol, remoxipride, ritonavir, saquinavir, selegiline, tamsulosin, timolol, tomoxetine, tramadol, trifluperidol, zolpidem... 

Other examples of MIPs prepared for the separation of pharmaceuticals using methacryhc acid as functional monomer and ethylene glycol dimethacrylate as the crosslinker include the MIPs with caffeine templates for the extraction of the same from human plasma and tea [264] or MIPs with dipyridamole, methadone, citalopram. Propranolol, 3-methylflavone-8-carboxylic acid, dextromethorphan, benzodiazepines, methamphetamine, hydrochlorothiazide, tolazoline, tramadol, pseudoephedrine and promethazine templates for the extraction of the templates from urine, sahva and serum samples [266,270,271,274,275,277,279,280,284,287,288,290,291,292]. Further examples include MIPs of the same compositions prepared with dextromethorphan templates for... 

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