Circuitry associated with receptor

Figure 11. Possible molecular circuitry associated with receptor activation by a cat group I (dog class B) stimulant...

The authors suggested a causal association between use of marijuana and extrapyramidal disorders. The research literature contains evidence that the endogenous canna-binoid system plays a role in basal ganglia transmission circuitry, possibly by interfering with dopamine reuptake. Furthermore, central cannabinoid receptors are located in two areas that regulate motor activity, the lateral globus pallidus and substantia nigra (89). 

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