Cinnamaldehyde dimethylacetal

Cinnamaldehyde dimethylacetal is prepared by the method used to prepare the corresponding diethylacetal. A mixture of 66.0 g. (0.5 mole) of Aldrich Chemical Company, Inc.), 100 g. (1.06 mole) of trimethyl orthoformate (Eastman Organic Chemicals), 450 ml. of anhydrous methanol (J. T. Baker Chemical Company), and 0.5 g. ofp-toluenesulfonic acid monohydrate (Fisher Scientific Company) is stirred at room temperature for 24 hours. At the end of this time the alcohol is removed with a rotary evaporator and the residue is distilled to give 81-83 g. (91-93%) of cinnamaldehyde dimethylacetal, b.p. 93—96° (0.2 mm.). 

CHROMIUM TRIOXIDE-PYRIDINE COMPLEX, preparation in situ, 55, 84 Chrysene, 58,15, 16 fzans-Cinnamaldehyde, 57, 85 Cinnamaldehyde dimethylacetal, 57, 84 Cinnamyl alcohol, 56,105 58, 9 2-Cinnamylthio-2-thiazoline, 56, 82 Citric acid, 58,43 Citronellal, 58, 107, 112 Cleavage of methyl ethers with iodotri-methylsilane, 59, 35 Cobalt(II) acetylacetonate, 57, 13 Conjugate addition of aryl aldehydes, 59, 53 Copper (I) bromide, 58, 52, 54, 56 59,123 COPPER CATALYZED ARYLATION OF /3-DlCARBONYL COMPOUNDS, 58, 52 Copper (I) chloride, 57, 34 Copper (II) chloride, 56, 10 Copper(I) iodide, 55, 105, 123, 124 Copper(I) oxide, 59, 206 Copper(ll) oxide, 56, 10 Copper salts of carboxylic acids, 59, 127 Copper(l) thiophenoxide, 55, 123 59, 210 Copper(l) trifluoromethanesulfonate, 59, 202... 

Fortier and Fritz [13] separated water by lEC and devised a unique equilibrium system for in-line spectrophotometric detection. This method has been refined and its capabilities expanded by continuing research by Chen and Fritz [14-17]. Water is separated chro-matographically from the other sample components on a short column packed with cation-exchange resin in the form using dry methanol as the eluent. Detection of the water peak is made possible by addition of a low concentration of cinnamaldehyde to the methanol eluent. In the presence of an acid catalyst, such as a -cation exchanger, cinnamaldehyde reacts with methanol to form the dimethylacetal. 

---