Cinamic acid

Chapter 4 - Propolis has been used for as a traditional medicine in Eastern Europe as an antifungal, antimicrobial, antiviral, anti-inflammatory, and anticarcinogenic agent. The author isolated three cinamic acid derivatives and one flavanol derivative from Brazilian propolis and determined their structures by spectroscopic analysis. Results were assayed, the anticancer drug potential of these compounds to identify new drug candidates, by determining the... 

Reaction 9.1 has been extensively studied to establish the mechanism of asymmetric hydrogenation. The catalytic cycle proposed for the asymmetric hydrogenation of the methyl ester of a-acetamido cinamic acid with 9.14 as the precatalyst is shown in Fig. 9.3. As mentioned earlier, this reaction is one of the early examples of industrial applications of asymmetric catalysis for the manufacture of L-DOPA (see Table 1.1). 

What are the similarities and differences in the behavior of a-acetamido-cinamic acid and allyl amine as ligands in asymmetric hydrogenation and isomerization reactions, respectively ... 

Then, the photopolymerizability of p-phenylenediacrylic acid (PDA) and its derivatives, which possess two cinamic acid units in a single molecule, was investigated for comparison with the crystalline-state photodimerization of cinnamic acid151. 

Cinamic acid ester 20 Cinamic acid ester P2O4 153)... 

Lignin precursors p-coumaryl (p-CA), coniferyl (CA) and sinapyl (SA) alcohols, are synthesized through the shikimate and cinamic acid pathways, starting from phenylalanine which under the action of phenylalanine ammonia-lyase (PAL) is deaminated followed by hydroxylations of the aromatic ring, methyla-tions and reductions of therminal acidic group to an alcohol leading to the formation of the monolignols (Fig. 8.2), [37, 48]. 

Pd-catalyzed reactions tolerate a great variety of functional groups (5). Vinyl benzamide or vinyl anilin are examples obtained in good yields and at polymerization-grade purity. By substitution of ethylene with acrylic acid derivatives products with cinamic acid structures are obtained (d). 

The coumarins, including the bronchodilator and vasodilator furanecoumarins, are a class of natural products that are found in many plants. They are structurally similar to lactones derived from o-cinamic acid, and 1,2-benzopyrone is the most simple example. Coumarins have been found to have a range of biological activities including anti-HIV, anticancer, vasodilator (anti-hypertension), anti-arrhythmia, anti-osteoporosis, bronchodilator (for treatment of asthma), and antisepsis properties. The solid-phase synthesis of coumarins (and the related isocoumarins) was reviewed by Correa and colleagues in their review of solid-phase natural product synthesis, and both the solid-phase synthesis of coumarins, and derivatization of supported coumarin... 

Min, J., Meng-Xia, X., Dong, Z., Yuan, L., Xiao-Yu, L., and Xing, C. (2004). Spectroscopic studies on the interaction of cinamic acid and its derivatives with human serum albumin. J. Mol Struct., 692, 71-80. 

Biosyntheses of the B. are numerous and at least 6 different routes leading to B. are known. Thus, 2-methoxybenzoquinone and the glucoside of benzohydro-quinone arbutin are formed by / -oxidation of cinam-mic acid or its derivatives. On the other hand the B. nucleus of the plastoquinones arises from homogen-tisic acid while the lipophilic side chain is built up from mevalonic acid. Structurally very similar B. can be formed from completely different precursors (acetate or p-hydroxybenzoate) in the same fungal organism Lit Czygan (2.), p. 356. Z. Pfianzenphysiol. 59,439 (1968). Luckner (3.). p. 415. 

Definition Ammonium salt of a lauryl alcohol half ester of sulfosuccinic acid ionic Nature Anionic Empirical C gHjoOjS 2H3N Formula CH3(CH2),pCH20COCHS03NH4CH2COONH4 Uses Surfactant, skin conditioner, foaming agent in cosmetics Manuf/Distrib. Somerset Cosmetic Co. Variati Diammonium octadecyl sulfosuccinamate. See Diammonium stearyl sulfosuc-cinamate... 

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