Solutions ciclopirox topical

Each gram of PENLAC NAIL LACQUER (ciclopirox) topical solution, 8%, contains 80 mg ciclopirox in a solution base consisting of ethyl acetate, isopropyl alcohol,... 

Ciclopirox topical (Penlac) solution is a nail lacquer that is PDA approved for the treatment of onychomycosis but demonstrates low complete cure rates. 

Ciclopirox is also sold as a 0.77% gel and a 1% shampoo for the treatment of seborrheic dermatitis of the scalp, and an 8% topical solution (PENIAC NAIL LACQUER) is sold for the treatment of onychomycosis. 

Gupta AK, Fleckman P, Baran R. Ciclopirox nail lacquer topical solution 8% in the treatment of toenail onychomycosis. 

Pharmacokinetic studies indicate that 1-2% of the dose is absorbed when applied as a solution on the back under an occlusive dressing. Ciclopirox olamine is available as a 1% cream and lotion (Loprox) for the topical treatment of dermatomycosis, candidiasis, and tinea versicolor. The incidence of adverse reactions has been low. Pruritus and worsening of clinical disease have been reported. The potential for delayed allergic contact hypersensitivity appears small. 

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