Chymodiactin - Chymopapain

Chymodiactin chymopapain, chymopapain [ban, inn, usan) (NSC 107079 BAX 1526 Chymodiactin ) is an ENZYME (MW c. 27,000) isolated from Carica papaya (papaya). It is a proteolytic enzyme, used by injections into vertebral discs to treat sciatica and lumbar pain (herniated lumbar discs). 

In eastern Europe. Letoozim , a mixture of the papaya proteinases, is used for the treatment of eye burns [115] as well as for some cases of cataract [1161. Recently, a new application for chymopapain has been reported, Chymodiactin has been used in the process of removal of tumor cells from autologous marrow grafts in a positive selection system [117,118], This process clears the way for the use of autologous bone marrow transplants in the treatment of several types of cancer, since the authors showed tlst hemopoietic stem cells, the nrecyr ors of al lymphohemopoietic lineages, are present in cell mixtures purified in this way [119],... 

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