Chylomicrons definition

By definition, chylomicrons are found in chyle formed only by the lymphatic system draining the intestine. They are responsible for the transport of all dietary lipids into the circulation. Small quantities of VLDL... 

Data have indicated that chylomicron phospholipids (Havel and Clark, 1958 McCandless and Zilversmit, 1958 Minari and Zilversmit, 1963), free cholesterol (Minari and Zilversmit, 1963), and protein (Hoffman, 1960 Scanu and Page, 1961) undergo an exchange or transfer process with the corresponding components of soluble lipoproteins, leading to either a net loss or renewal of these fractions in chylomicrons prior to their removal from pla.sma. The degree of modification of the chylomicron particles by lipoproteins of circulating plasma is worth definition since it bears directly on the problem of their uptake. 

The lipoproteins present in plasma may be operationally defined according to their density, as low or very low density lipoproteins and high density lipoproteins, but other, more functional definitions may be more appropriate in connection with in vivo metabolism. Examples are the hpoprotein classes chylomicrons and chylomicron remnants. Alaupovic has suggested a classification based on the apolipoprotein composition [1]. As apolipoproteins often determine the metabolic fate of lipoprotein particles this is a logical approach. Lipoprotein particles with specific apolipoprotein compositions exist in all density fractions of human plasma, as well as plasma from a variety of animal species. 

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