Chromone glycoside

Cassia multijuga Rich. -topeiuia As a sedative for children Leaves Tenharins Indians [56] Anthraquinones [315,316] anthraquinones glycosides [317] chromone glycosides [318,319] flavonol glycoside [320] ... 

Pyran-4-one, 2,2,5-trimethyl-2,3-dihydro-photodimerization, 3, 720 4H-Pyran-4-one, 2,3-dihydro-2,3,5-trimethyl-6-( 1 -methyl-2-oxobutyl)-synthesis, 3, 844 Pyranones alkylation, 2, 56 aromaticity, 3, 632, 633 C NMR, 3, 587, 635 H NMR, 3, 580 cardiac glycosides, 3, 883 chromone synthesis from, 3, 830 colour couplers... 

An anti-snake venom principle has recently been reported as a glycosidal quaternary chromone alkaloid named schumanniofoside 36 (14). Extracts of the stem bark were tested against the venom of the black cobra, Naja melanoleuca, in mice. The methanolic extract showed the greatest activity. This was fractionated and monitored to yield 36 as the active component. 

Cui, C-B. et al.. Constituents of a fern, Davallia mariessi Moore. IV. Isolation and structures of a novel norcarotane sesquiterpene glycoside, a chromone glucuronide, and two epicatechin glycosides, Chem. Pharm. Bull, 40, 2035, 1992. 

The red, violet, and blue pigments of flower petals are called anthocyanins, and are glycosides of various benzopyrilium cations. Delphinidin chloride 9.7, for example, is a blue pigment. Khellin 9.8 is a natural product which has found clinical application in the treatment of bronchial asthma and has been the starting point for the design of many totally synthetic chromones with improved biological properties. 

Tanaka, T., Orii, Y., Nonaka, G. and Nishioka, I. (1993) Tannins and related compounds. CXXIII. Chromone, acetophenone and phenyl propanoid glycosides and their galloyl and/or hexahydroxy phenoyl esters from leaves of Syzygium aromaticum Merr and Perry. Chemical Pharmaceutical Bulletin 28, 685-687. 

Flavonol glycosides (flavinoids) such as rutin, hesperidin, and querectin, which contain the chromone ring system, were found to have AR-inhibiting activity. Querectin was the most potent. 

---