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Choline dehydrogenase

Succinic dehydrogenase , "NADH-dehydrogenase", "Choline dehydrogenase ,... [Pg.3]

The existence of choline dehydrogenase was first demonstrated by Mann and Quastel in 1937 247, 248) in extracts of rat liver and kidney. These authors also obtained evidence that the first oxidation product of choline was betaine aldehyde. Others showed subsequently that choline oxidase activity resided in the mitochondrial fraction of rat liver and is linked to the respiratory chain 249, 250). Detergents 251, 252), solvent treatment of fragmented mitochondria 253), and venom phospholipase 254-256) have been used for extraction and solubilization of choline dehydrogenase. Among these, the best method reported to date appears to be the digestion of acetone-powdered mitochondria with venom phospholipase. Choline dehydrogenase, partially purified from phospholipase extracts of rat liver mitochondria, contains 1 mole of flavin and 4 g-atoms of nonheme iron per 850,000 g protein. The flavin is claimed to be acid-... [Pg.260]

It was shown by Strength et al. (261) that the oxidation of choline by a particulate preparation from rat liver was considerably enhanced upon addition of NAD. Others showed that choline oxidation by isolated rat liver mitochondria was completely inhibited by Amytal when oxygen, cytochrome c, ferricyanide, or methylene blue was the electron acceptor -264) Choline dehydrogenase activity of particles and soluble prepa-... [Pg.261]

Adenosine triphosphatase cytochrome c oxidase and, 321 transhydrogenase and, 79 Adenosine triphosphate choline dehydrogenase and, 263 cytocrome c oxidase and, 300, 302, 343 glyceraldehyde-3-phosphate dehydrogenase and, 25, 26, 48, 49 lipoamide dehydrogenase and, 125 NADH dehydrogenase and, 207 redox potentials and, 215, 216 succinate dehydrogenase and, 247, 248, 249... [Pg.436]

Betaine, formation of, 260 Betaine aldehyde, choline dehydrogenase and, 261, 262... [Pg.437]

NADH dehydrogenase and, 189 ubiquinone reductase and, 178,182,183 Cholesterol, side chain cleavage, 83, 84-85 Choline, oxidation to betaine, 260 Choline dehydrogenase electron transport system and, 261-263 properties, 260-201 Chromatium sulfate reduction by, 281 transhydrogenase of, 54 function of, 80 molecular properties, 58, 69 purification, 55, 56 Chromium... [Pg.438]

Dichlorophenolindophenol choline dehydrogenase and, 261 cytochrome 6j and, 267 cytochrome P-450 reductase and, 167 a-glycerophosphate dehydrogenase and,... [Pg.441]

Figure 14.4. Catabolism of choline. Choline dehydrogenase, EC 1.1.99.1 betaine aldehyde dehydrogenase, EC 1.2.1.8 and homocysteine methyltransferase, EC 2.1.1.5. Relative molecular masses (Mr) choline, 104.2 betaine, 117.2 dimethylglycine, 102.2 methylglycine, 88.2 and glycine, 74.2. THF, tetrahydrofolate. Figure 14.4. Catabolism of choline. Choline dehydrogenase, EC 1.1.99.1 betaine aldehyde dehydrogenase, EC 1.2.1.8 and homocysteine methyltransferase, EC 2.1.1.5. Relative molecular masses (Mr) choline, 104.2 betaine, 117.2 dimethylglycine, 102.2 methylglycine, 88.2 and glycine, 74.2. THF, tetrahydrofolate.
See other pages where Choline dehydrogenase is mentioned: [Pg.101]    [Pg.39]    [Pg.52]    [Pg.102]    [Pg.147]    [Pg.175]    [Pg.176]    [Pg.260]    [Pg.261]    [Pg.262]    [Pg.435]    [Pg.436]    [Pg.436]    [Pg.437]    [Pg.438]    [Pg.439]    [Pg.439]    [Pg.440]    [Pg.442]    [Pg.443]    [Pg.443]    [Pg.443]    [Pg.444]    [Pg.448]    [Pg.448]    [Pg.448]    [Pg.448]    [Pg.449]    [Pg.449]    [Pg.450]    [Pg.451]    [Pg.451]    [Pg.451]    [Pg.451]    [Pg.452]    [Pg.452]    [Pg.454]    [Pg.454]    [Pg.454]    [Pg.457]   
See also in sourсe #XX -- [ Pg.391 ]

See also in sourсe #XX -- [ Pg.391 ]

See also in sourсe #XX -- [ Pg.391 ]

See also in sourсe #XX -- [ Pg.164 ]



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