Cholesteryl-pullulan

W. Yang, M. Wang, L. Ma, H. Li, and L. Huang, Synthesis and characterization of biotin modified cholesteryl pullulan as a novel anticancer drug carrier, Carbohydr. Polym., 99, 720-727, 2014. 

Because the micellar interior is far from being rigid, a solubilized substrate is relatively mobile. Like micelle formation, solubilization is a dynamic equilibrium process. Representative recent examples are the solubilization of benzene, naphthalene, anthracene, and pyrene in aqueous solution by the addition of 1-dodecanesulfonic acid [391], the solubilization of fullerene Ceo in aqueous solutions of the non-ionic surfactant Triton X-100 [392], and the solubilization of a cholesteryl-group bearing pullulane (a hydrophobized polysaccharide) [393]. 

Coating of emulsion particles with cholesterol-bearing polysaccharides, such as pullulan, amylopectin, and mannan, led to a reduction of the divalent metal ion-induced aggregation of Che emulsion droplets. The cholesteryl group behaves as a hydrophobic anchor in the surface lipid layer resulting in a lower fluidity of the. surface of the emulsion droplets (24). 

Regular surface-rehef calcium carbonate structures were prepared by a cooperated directing agent of soluble poly(acryhc acid) (PAA, Mw = 2000) and a substrate of cholesterol-bearing pullulans (Fig. 15) [231]. At low temperature, adapted PAA concentration, and with cholesteryl groups, a high quality periodic calcite structure can be formed by a self-organization process in the reaction-diffusion system with competition between precipitation and ion diffusion. 

Fujioka-kobayashi, M., Ota, M.S., Shimoda, A., Nakahama, K., Akiyoshi, K., Miyamoto, Y, Iseki, S., 2012. Cholesteryl group and acryloyl group-bearing pullulan nanogel to dehver BMP2 and FGF18 for bone tissue engineering. Biomaterials 33, 7613-7620. 

Pullulan, carboxymethylcellulsoe, glycol chitosan, sodium alginate Cholesteryl residue 40-41,46,52-56... 

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