Chlorpyrifos urinary monitoring

The absorbed dose or body burden of chlorpyrifos can be estimated using urinary monitoring data as follows 3... [Pg.26]

Comparison of exposure levels — total absorbed dose of chlorpyrifos (passive dosimetry vs. urinary monitoring)... [Pg.31]

To monitor the absorbed chlorpyrifos doses in human volunteers, urine was collected before and following a 4-hr activity period on the treated grass surface(re-entry). The urine was analyzed for 3,5,6-trichloropyridinol (3,5,6-TCP), the urinary metabolite of chlorpyrifos, and creatinine, which was determined to verify completeness of urine collection by each volunteer. [Pg.51]

Chlorpyrifos provides an example of the utility of human pharmacokinetic models to estimate daily dose from biomonitoring data for a rapidly cleared pesticide. The urinary metabolite trichloro-2-pyridinol (TCP) is used in the NHANES study to monitor population exposure to chlorpyrifos (CDC 2005). Several epidemiologic studies have linked chlorpyrifos exposure to adverse birth outcomes through associations between urinary and blood biomarkers and have demonstrated maternal exposure and physiologic measurements in the neonate (Berkowitz et al. 2003, 2004 Whyatt et al. 2004 Needham 2005). [Pg.295]

Urinary Metabolite Monitoring 28 Salivary Monitoring 29 VALIDATION OF PASSIVE DOSIMETRY 30 Atrazine 30 Chlorpyrifos 31... [Pg.13]

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