Chlorpromazine, cyanide poisoning

Pettersen JC and Cohen SD (1985). Antagonism of cyanide poisoning by chlorpromazine and sodium thiosulfate. Toxicol Appl Pharmac, 81, 265-273. 

In addition, other chemicals such as a-adrenergic blocking agents like chlorpromazine (O Flaherty and Thomas 1982 Way and Burrows 1976) or oxygen (Burrows et al. 1973 Sheehy and Way 1968) may be used to enhance the protective action of other antidotes. However, the mechanism of their action is not well understood. Further research for a potent and safe antidote, particularly among smoke inhalation victims who have carbon monoxide poisoning, to mitigate cyanide toxicity is desirable. 

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