3-adrenergic blocking agent

Adrenergic blocking agent. A drug that blocks the effects of epinephrine and/or norepinephrine. 

Therapeutic Function Adrenergic blocking agent for cardiovascular problems... 

There is a decreased effectiveness of ritodrine when the drug is administered with a -adrenergic blocking agent such as propranolol and an increased risk of pulmonary edema when administered with the corticosteroids. Co-administration of ritodrine with the sym-pathomimetics potentiates the effect of ritodrine. Cardiovascular effects (eg, arrhythmias or hypotension) of ritodrine may increase when the drug is administered with diazoxide, general anesthetics, magnesium sulfate, or meperidine... 

Palytoxin (PTX), isolated from the zanthid Palythoa species, caused a rapid contraction followed by a slow phasic contraction of the guinea pig vas deferens. The second component of PTX-induced contraction was markedly inhibited by adrenergic blocking agents, whereas the first component was blocked by ouabain. In pheochromocytoma cells,... 

The nonselective ]3-adrenergic blocking agent that is also a competitive antagonist at aradrenoceptors is... 

The mainstay of primary prophylaxis is the use of nonselective / -adrenergic blocking agents such as propranolol or nadolol. These agents reduce portal pressure by reducing portal venous inflow via two mechanisms decrease in cardiac output, and decrease in splanchnic blood flow. They prevent bleeding, and there is a trend toward reduced mortality. 

Excellent asymmetric hydrogenation of amino ketones has been applied for the syntheses of many chiral drugs. For example, the enantioselective hydrogenation of 3-aryloxy-2-oxo-l-propylamine derivatives can directly afford the l-amino-3-aryloxy-2-propanol derivatives as chiral / -adrenergic blocking agents. This has been successfully accomplished with a neutral MCCPM-Rh complex as the catalyst. With 0.01 mol.% of an (A,A)-MCCPM-Rh complex,... 

Hydralazine is usually used in combination with other drugs. In recent years, it has been found to be especially useful when used with beta-adrenergic blocking agents and diuretics (3,4). 

In addition, other chemicals such as a-adrenergic blocking agents like chlorpromazine (O Flaherty and Thomas 1982 Way and Burrows 1976) or oxygen (Burrows et al. 1973 Sheehy and Way 1968) may be used to enhance the protective action of other antidotes. However, the mechanism of their action is not well understood. Further research for a potent and safe antidote, particularly among smoke inhalation victims who have carbon monoxide poisoning, to mitigate cyanide toxicity is desirable. 

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