Phenylpropanolamine chlorpheniramine, dextromethorphan

V. Das Gupta and A. Helbe, Quantitation of acetaminophen, chlorpheniramine maleate, dextromethorphan hydrobromide, and phenylpropanolamine hydrochloride in combination using high-performance liquid chromatography, J. Pharm. Sci., 75 1553 (1984). 

Simultaneous acetaminophen, acetophenazine, amoxapine, amphetamine, atropine, ben-peridol, buspirone, caffeine, carbamazepine, chlorpheniramine, codeine, dextromethorphan, diazepam, diphenhydramine, flupenthixol, flurazepam, heiloperidol, hydergine, hy-drocodone, hydromorphone, lidocaine, loxapine, mepazine, meperidine, mesoridazine, methaquaalude, 3,4-methylenedioxyamphetamine, 3,4-methylenedio30 ethylamphetam-ine, 3,4-methylenedioxymethamphetamine, morphine, norcocaine, oxazepam, pentobarbital, phenylpropanolamine, procainamide, procaine, propyl benzoylecgonine, quinidine, quinine, salicylic acid, secobarbital, theophylline, trazodone, 3-tropanyl-3,5-dichloroben-zoate, vancomycin, WIN 35428... 

Figure 5.9 Resolution of acetaminophen (a), phenylpropanolamine (b), chlorpheniramine (c), and dextromethorphan (d) by silica gel using methanol, water, and phosphate buffer at pH-7.8. (Courtesy of Journal of Pharmaceutical Sciences.)...

Oral solution containing at least three of the following—Acetaminophen and salts of Chlorpheniramine, Dextromethorphan, and Phenylpropanolamine USP (24, p. 24)... 

Pennkinetic System Skye Pharma AG, Muttenz, Switzerland The system combines CR principles of ion exchange with membrane diffusion. The system is made up of an ion-exchange polymer-drug complex as a core material, which is subsequently coated with ethylcellulose to form a water insoluble but permeable coating. Release rates are relatively constant and unaffected by variable conditions of the GI tract. The system can be formulated in capsule form as well as suspensions. Delsym (Dextromethorphan), Corsym (Chlorpheniramine) and Cold Factor 12 (Phenylpropanolamine). 

Noninterfering amitriptyline, amphetamine, atropine, benzoylecgonine, benztropine, caffeine, carbamazepine, carisoprodol, chlorpheniramine, chlorpromazine, chlorprothixene, cimetidine, cocaine, codeine, dextromethorphan, diazepam, diphenhydramine, diphenox-ilate, disopyramide, doxepin, dojylamine, emetine, erythromycin, flurazepam, gluteth-imide, hydrocortisone, hydromorphone, hydroxyzine, imipramine, lidocaine, loxapine, meperidine, meprobamate, methadone, methamphetamine, methapyrilene, methaqualone, methocarbamol, methylphenidate, nicotine, nordiazepam, nortriptyline, orphenadrine, papaverine, pentazocine, phenacetin, phencyclidine, phenmetrazine, phenolphthalein, phentermine, phenylpropanolamine, phenytoin, prazepam, procaineimide, procaine, propoxyphene, propranolol, protriptyline, pseudoephediine, pyrilamine, quinine, salicylam-ide, spironolactone, strychnine, terpin hydrate, thioridazine, thiothixene, triamterene, trifluoperazine, triflupromeizine, trihexyphenidyl, trimeprazine, trimethobenzamide, trimethoprim, tripeleimamine... 

Romanyshjm, L.A. Wichmann, J.K. Kucharczyk, N. Shumaker, R.C. Ward, D. Sofia, R.D. Simultaneous determination of felbamate, primidone, phenobarbital, carbamazepine, two carbamazepine metabolites, phenytoin, and one phenytoin metabolite in human plasma by hig -performance liquid chromatography. Ther.Drug Monit., 1994,16,90-99 [plasma extracted metabolites, felbamate, phenobarbital, primidone column temp 40-50 LOQ 195-391 ng/mL simultaneous acetaminophen, aspirin, brompheniramine, caffeine, chlorpheniramine, dextromethorphan, dimethadione, ethosuximide, ethotoin, ibuprofen, iministUbene, mephenytoin, mephobarbital, metharbital, methsuximide, para-methadione, phenacemide, phensuximide, phenylpropanolamine, theophylline, trimethadione noninterfering clonazepam valproic acid]... 

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