Chitosan structure-property relationship

Domard, A., Domard, M., 2002. Chitosan Structure-properties relationship and biomedical application. In Dumitriu, S. (ed.) Polymeric Biomaterials. Marcel Dekker, New York, pp. 187-212. 

Koping-Hoggard M, Tubulekas I, Guan H, Edwards K, Nilsson M, Varum KM, Artursson P (2001) Chitosan as a nonviral gene delivery system. Structure-property relationships and characteristics compared with polyethylenimine in vitro and after lung administration in vivo. Gene Ther 8 1108-1121... 

Einbu A, Varum KM (2004) Structure-property relationships in chitosan. In Reference 10, p217... 

In this chapter, we first discuss the chemical and physical properties of chitosan, including the synthesis, modification, molecular structure, characterization, and structure-property relationship. Second, we review the topics of biocompatibility, biodegradability, and antimicrobial activity of chitosan. These properties make chitosan a potential biomaterial for many biomedical applications. 

Other studies provide a basic structure-property relationship analysis for ethylcel-lulose/chitosan blends applications in the film and fiber industry [141] by means of Fourier transition infrared spectra, wide-angle X-ray diffraction, differential scanning calorimetry, scanning electronic microscopy, polarizing light microscopy. Thus,... 

Structure and Property Relationship 97 5.6 Chitosan Application in Drug Delivery 106... 

Knowledge of the microstructure of chitosan samples is essential for understanding the structure-property-activity relationships of chitin and chitosan products [ 18,38-42]. To date, only the effect of weight-averaged molecular weight (MW) and degree results... 

Depan D, Misra RDK. The interplay between nanostructured carbon-grafted chitosan scaffolds and protein adsorption on the ceUnlar response of osteoblasts structure-function property relationship. Acta Biomater 2013 9 6084. 

J2 CHITOSAN AS BIOMATERIAL STRUCTURE-PROPERTY-FUNCTION RELATIONSHIP... 

Depan D, Shah JS, Misra RDK. Degradation mechanism and increased stability of chitosan-based hybrid scaffolds cross-linked with nanostructured carbon process-structure-functional property relationship. Polym Degrad Stab 2013 98 (11) 2331. 

Koping-Hoggard et al. [68] established the relationships between the structure and the properties of chitosan-pDNA polyplexes in vitro and in vivo. They compared polyplexes of ultrapure chitosan (UPC) of preferred molecular structure with those of polyethylenimine (PEI) polyplexes in vitro and after intratracheal administration to mice in vivo. UPC carriers were less cytotoxic than polyethylenimine (PEI) polyplexes and provided a better efficiency compared with that of commonly used cationic lipids. Low-molecular weight chitosan delivery systems were more efficient for cell transfection and less cytotoxic compared with PEL [65]. 

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