Chitin deposition

Benzoylphenyl Ureas—A New Group of Larvicides Interfering with Chitin Deposition... 

From the results discussed so far it can be concluded that diflubenzuron interferes very rapidly with chitin deposition. The possible effects on the deposition of protein, the second important component of the endocuticular matrix, were studied by Hunter and Vincent with adult locusts (.44). It was concluded that protein deposition was completely unaffected as regards the quantity of protein found. Another conclusion was that cross-linking of the protein - as revealed by the differing solubilities of the protein fractions - was also unaffected. Deul et al. (45)... 

These are haloaromatic substituted ureas which controls insects by impairing chitin deposition in the larval exoskeleton. They are formulated in wettable powders, oil dispersible concentrates, and granules for in agriculture and forestry and in settings where fly populations tend to be large, such as feed-lots. 

Verloop A, Ferrell CD. Benzoylphenyl ureas - a new group of latvicides interfering with chitin deposition. ACS Symp. Ser. 37 (Pestic. Chem. 

Synonyms N-((4-Chlorophenyl) aminocarbonyl)-2,6-difluorobenzamide 1-(4-Chlorophenyl)-3-(2,6-difluorobenzoyl) urea Difluron Dimilin Empirical C14H9CIF2N2O2 Properties Cryst. m.w. 310.70 m.p. 230-232 C Toxicology LD50 (oral, rat) 4640 mg/kg, (skin, rabbit) 2000 g/kg mod. toxic by skin contact mildly toxic by ing. mutagen TSCA listed Hazardous Decomp. Prods. Heated to decomp., emits very toxic fumes of Cl, F, NOx Uses Insecticide interfering with chitin deposition used for forestry ornamentals, fruit, field crops, horticulture, etc. 

Action Insecticide, larvicide, ovicide insect growth regulator acting by interference with deposition of insect chitin... 

Diflubenzuron (Dimilin , TH-6040) is an IGR which inhibits the normal deposition of chitin. The metabolic fate of diflubenzuron has been studied in sheep U, 2), cattle (1 ), rats (1, 3), house flies (4, 5), stable flies (5), chickens (6), swine (6), boll weevils (7), plants (8 9), and soil (2, 8, 10). Since good reviews of diflubenzuron metabolism have been given by Ivie (11) and Verloop and Ferrell (9), we will present only a tabular summary of the degradation of diflubenzuron in nonaguatic systems for comparative purposes (Table I). The remaining discussion will focus on diflubenzuron degradation in the aquatic environment. 

A number of invertebrates deposit phosphate in their shell structures24. In the articulate brachiopod shell — Lingula — apatite crystallites occur up to about 1000 A long. Little is known, however, on the nature of shell organic matter, except that the amount of chitinous material exceeds that of protein fraction by a factor of two408. ... 

Its fungicidal action is based on ergosterol depletion and the accumulation of ignosterol in fungal cytoplasmic membrane, which causes the fungal cell wall to thicken and chitin to be deposited. 

A very complicated exoskeleton is excreted by arthropods, consisting of many layers of proteins and lipids and a nitrogen-containing polysaccharide known as chitin. The more massive, rigid parts of arthropod exoskeletons are strengthened by the deposition of calcium carbonate in their middle layers or by the tanning of the proteins by cross-linking of the protein chains by orthoquinones. 

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