Chirality scaffolding crystallization

Compound 2a usually crystallizes to produce racemic crystals. However, we have recently succeeded in obtaining chiral crystals of 2a in the presence of certain organic compounds and called this chirality scaffolding crystallization. ... 

Complementary dendritic hexamers based on a central scaffold made up of linked pentaerythritol and tri(hydroxymethyl)amino methane units have been found to also exhibit liquid-crystalline properties. This star-shaped scaffold was used to create supermolecules containing two different hemispheres, referred to thereafter as Janus supermolecular Hquid crystals (Fig. 76) [323,324]. One of the hemisphere contains three cyanobiphenyl end-groups, whereas the other lobe consists of three chiral phenyl benzoate mesogenic moieties laterally attached. The type of mesophase observed (N ... 

Over the last three decades, chiral carbon-rich compounds have evolved into an interesting and useful class of materials due to the many unique properties that result from the installation of conjugated chromophores within a chiral framework. Chiral carbon-rich materials possess distinct chirooptical and electronic properties that may prove useful for a number of intriguing applications ranging from optically active liquid crystals to nonlinear optical materials. Chiral carbon-rich compounds also represent a potentially valuable scaffold for use in asymmetric reactions and catalysis. 

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