Chirality biological relevant systems

Chiral Ln(III) Complexes to Probe Biologically Relevant Systems... 

Unlike the Pfeiffer-induced systems discussed in Section 3.4.1, this section details some of the successful recent examples demonstrating the design principles for targeting anions and/or proteins that are of biological relevance [direct coordination to the metal centre of the chiral Ln(III)-based probes], followed by a survey of similar studies for analyte sensing (i.e. cations and/or proteins) in which the coordination occurs between the analytes and some of the antenna/receptor groups of the chiral Ln(III)-based probes. 

Carbohydrates, similarly to peptides, are natural sources of chirality and also offer a wide range of ncm-covalent interactions. Molecular recognition of carbohydrates by biological receptors mediates a variety of physiologically relevant processes, including recruitment of leucocytes to inflammatory sites, clearance of glycoproteins from the circulatory system, cell interactions in the immune system, as well as adhesion of bacteria or viruses to host cells. It has been shown that multivalency is especially important for carbohydrate-receptor interactions. The glycoside cluster... 

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