Chemogenomics

Ganter B, Tugendreich S, Pearson Cl, Ayanoglu E, Baumhueter S, Bostian KA, et al. Development of a large-scale chemogenomics database to improve drug candidate selection and to understand mechanisms of chemical toxicity and action. J Biotechnol 2005 119 219-44. 

Bredel M, Jacoby E. Chemogenomics An emerging strategy for rapid target and drug discovery. Nat Rev Genet 2004 5 262-75. 

Mestres J. Computational chemogenomics approaches to systematic knowledge-based drug discovery. Curr Opin Drug Discov Dev 2004 7 304-13. 

Savchuk NP, Balakin KV, Tkachenko SE. Exploring the chemogenomic knowledge space with annotated chemical libraries. Curr Opin Chem Biol 2004 8 412-17. 

Figure 2.18 Chemogenomic analysis of targets BioPrint targets clustered in chemical space by fingerprint of activities against the consistent BioPrint compound set.

Chemogenomics Knowledge-Based Approaches to Drug Discovery (ed. E. Jacoby), Imperial College Press, London, pp.175-206. 

Small Molecules for Chemogenomics-based Drug Discovery... 

Table 1 Commercially and Publicly Available Compound Databases and Molecular Informatics Resources (see Section 5) for Chemogenomics Research. The list is not exhaustive, but rather constitutes a representative compilation of selected examples in this field.

Designing Comprehensive Chemogenomics Screening Compound Collections... 

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