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Target Family-directed Masterkeys in Chemogenomics

Brand name Ingredient Company Indication Sales (growth) [ billion] [Pg.8]

Celebrex Celecoxib Pharmacia/Pfizer pain, arthritis 3.1 (32%) [Pg.8]

Nexium Esomeprazole AstraZenec ulcers proton pump inhibitor 623 (999%) [Pg.9]

Protonix Pantoprazole Altana/Wyeth ulcers proton pump inhibitor 695 (426%) [Pg.9]


Muller G. (2004) Target family-directed masterkeys in chemogenomics. In H Kubini, G Muller (eds), Chemogenomics in Drug Discovery—A Medicinal Chemistry Perspective, pp. 7-42. Wiley-VCH, Weinheim. [Pg.34]


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Chemogenomics

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Target family-directed masterkeys

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