Chase-off

FIGURE 2—48. Other drugs are reversible enzyme inhibitors, depicted as binding to the enzyme with a string. It is possible for the inhibitor to be chased off the enzyme under the right circumstances, in which case the inhibition is reversed and the enzyme becomes fully functional again. 

Genevieve smiled again, then spurred her horse on ahead, laughing gladly. Merlin, their sheepdog, chased off after her, kicking up whirling flurries of brown petals. 

Improvement will not come from policies based on the precautionary principle or any similar principle, which ignores the specifics of different risks and the benefits that accompany the substance or process that is being examined. Good policy cannot be derived by skipping over the fact that we live in a world of trade-offs and that actions have consequences. A regulatory and policy system that produces greater value for society must have a foundation of credibility. Far better to emphasize science in the risk assessment process and to examine the process and evaluate how well it works than to chase after lofty aspirations embodied in a principle without definition. 

Lavoisier was an arrogant man. He was often accused of not giving credit to others, a criticism he shrugged off with the casual explanation, The one who chases the hare is not always the one who eats the stew. But he transformed the science of chemistry from an archaic and eclectic array of theories and reactions to a modern, systematic discipline. And he lost his head not once, but twice. 

Enter the reversible MAO inhibitors. If someone eats cheese, tyramine will still release sympathomimetic amines, but these amines will chase the reversible inhibitor off the MAO enzyme, allowing the dangerous amines to be destroyed (Fig. 6—24). This is sort of like having your cake—or cheese—and eating it, too. The reversible MAO inhibitors have the same therapeutic effects as the suicide inhibitors of MAO, but without the likelihood of a cheese reaction if a patient inadvertently takes in otherwise dangerous dietary tyramine. 

Gervin M, Hughes R, Bamford L, Smyth BP, Keenan E. Heroin smoking by chasing the dragon in young opiate users in Ireland stability and associations with use to come down off Ecstasy . J Subst Abuse Treat 2001 20(4) 297-300. 

Water, gas, electrical and drain lines are contained in chases which run vertically between floors on either side of the hall. Outside each laboratory there is a locked access panel in the chase, the key to which is kept in the laboratory. In an emergency any utilities to a single laboratory may be shut off from this chase. Of course, the building is equipped with the usual array of smoke and heat detectors and fire alarms. 

Got it chasing another bastard poacher b the reserve last night. Someone made a try for a marsh harrier s nest fve been keeping an eye on. I set off after them and went arse over elbow on one ofthe trails. ... 

Monitors, like all lizards, are poikilothermic or coldblooded. They are most energetic after they have been heated by the morning sun, since their muscles work much more efficiently and easily when they are warm. Monitors can run quickly to chase down prey. When doing so they lift their body and tail clear off the ground. 

They separate themselves from the geometric web and are moving toward me. They all want to sit on my abdomen, but then I won t be able to breathe. Strangely, although they look very light, they are actually quite heavy. It s incredible how heavy they are. I chase them off my abdomen and lie on my side. Immediately I feel better. The little beings become irresistibly funny and even somewhat disrespectful, which I really like. 

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