Characterization of drug-loaded textile materials

The morphology and mechanical properties, degradation properties, drag-loading efficiency, and release properties can be tested by using a variety of analytical techniques both in vitro and in vivo. Some of these test procedures are described below. 

Drug-loaded medical textiles are composite materials in which the textile structure serves as the base material. Many traditional test procedures can be applied to the characterization of the base material. For example, the morphology of the fabric surface can be characterized by using microscopic techniques, including optical microscopy, scanning electron microscopy, and atomic force microscopy, which provide useful 

As far as interface reactions are concerned, the drug-loaded fibers will present no problems as long as the chosen polymers are considered to be safe, although the incorporation of drugs may have some effect on the properties of the base materials. One possibility would be the occurrence of surface modifications, which could be disadvantageous in respect of interface reactions. 

Skin surface Interaction with sweat, sebum, wound exudate, xenobiotic materials, bacteria/viruses, fungi 

Wound/wound bed Binds to protein and wound debris absorbed by cells of wound margin 

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