Chance, Britton

Chan, Shirley S., and Austin, Robert H., Laser Photolysis in Biochemistry. .. Chance, Britton, see Maehly, A. C. 

Maehly, A. C., and Chance, Britton, The Assay of Catalases and Peroxidases. 1... 

Britton Chance, Department of Biochemistry/ Biophysics, University of Pennsylvania, Philadelphia, Pennsylvania, USA Steven Chu, Department of Physics,... 

With the help of spectrophotometric techniques, Britton Chance and others showed that any of the normal respiratory substrates can reduce all of the cytochromes in the membrane. Either succinate or NADH-linked substrates also can reduce all of the UQ. The flavins, however, are reduced only partially by succinate but almost completely by a combination of succinate and malate. These observations fit the idea that all of the cytochromes and UQ are part of a common network to which various flavoprotein dehy-drogenases can feed electrons. 

D. DeVault, J. H. Parker, and Britton Chance, Nature 215 642 (1967). Evidence of tunneling in electronic conductance of bio-organisms. 

Benaron D, Bigio I, Sevick-Muraca E, Yodh AG, eds. Special issue honoring Professor Britton Chance. J Biomed Opt 2000 5 115. 

Dr. Helmut Beinert and Dr. Britton Chance kindly provided information in advance of publication. Support from US.P.H.S, grant No. HL-19680 from the National Heart and Lung Institute aided the preparation of this chapter. 

WINSLOW S. CAUGHEY BRITTON CHANCE L. ERNSTER J. lEUAN HARRIS YOUSSEF HATEFI J. B. HOEK J. RYDSTROM... 

BRITTON CHANCE BO MALMSTROM LARS ERNSTER VINCENT MASSEY... 

BRITTON CHANCE (363), Johnson Research Foundation, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania... 

A major breakthrongh in time resolution ( 1 ms), dynamic range ( unlimited ) and reduction of sample amount came with the development by Britton Chance of the stopped-flow techniqne see Rapid Scan, Stopped-Flow Kinetics), which is stUl widely used today. The stopped-flow techniques finds a major application in the... 

Crossover point. The precise site of action of a respiratory-chain inhibitor can be revealed by the crossover technique. Britton Chance devised elegant spectroscopic methods for determining the proportions of the oxidized and reduced forms of each carrier. This determiniation is feasible because the forms have distinctive absorption spectra, as illustrated in the adjoining graph for cytochrome c. You are given a new inhibitor and find that its addition to respiring mitochondria causes the carriers between NADH and QH2 to become more reduced and those between cytochrome c and O2 to become more oxidized. Where does your inhibitor act ... 

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