Challenges and Objectives

Bernal, R.H. Fowler, A Theory of water and ionic solution, with particular reference to hydrogen and hydroxyl ions. J. Chem. Phys. 1(8), 515—548 (1933) 

Effect of the ordered water on protein folding an off-lattice Go ( ) over-bar-like model study. Phys. Rev. E 79(3), 031925 (2009) 

Pompliano, E. Guamieri, Diverse fragment clustering and water exclusion identify protein hot spots. J. Am. Chem. Soc. 133(28), 10740-10743 (2011) 

Twomey, R. Less, K. Kurata, H. Takamatsu, A. Aksan, In situ spectroscopic quantification of protein-ice interactions. J. Phys. Chem. B 117(26), 7889-7897 (2013) 

Water water— an enduring mystery. Nature 452(7185), 291-292 (2008) 

---

In terms of zeolites, chiral pores exist only in a low-temperature form of zeolite /3 [112]. Therefore, zeolites are not inherently suitable for either enantiomeric separations or stereospecific catalysis. As noted recently by Ball [6], the development of a new generation of chiral porous material represents one of the major challenges and objectives that faces crystal engineering. Such materials could find widespread application. Furthermore, coordination polymers have the potential to be inherently catalytically active because the metal centers used as nodes could be selected for their known catalytic activity. The issue of how to design and build chiral porous solids is closely related to that of how to design and build polarity into a solid. The subject of polarity is discussed below. 

---