Nervous system central, drugs acting

Miscellaneous Central Nervous System Acting Drugs... 

In Chapter 1 we discussed how modern psychopharmacology is essentially the study of chemical neurotransmission. In this chapter we will become more specific and discuss how virtually all central nervous system (CNS) drugs act in one of two very specific ways on chemical neurotransmission first and most prominently as stimulators (agonists) or blockers (antagonists) of neurotransmitter receptors or second, and less commonly, as inhibitors of regulatory enzymes. 

Drugs with stimulating effect on the central nervous system acting on circulatory and respiratory centra in the medulla. 

S. R Gupta, QSAR studies on drugs acting at the central nervous system. Chem. Rev. 1989, 89, 1765-1800. 

The BBB is a complex cellular system which protects the central nervous system (CNS) by separating the brain from the systemic blood circulation. Drugs that act... 

Pirsidomine 135 has antiischaemic and antianginal properties, and is similar in action to molsidomine, undergoing bioactivation in vivo to compound 136 <1996MI4937>. Sydnocarb (mesocarb) 59 acts on the central nervous system (CNS) and has been used as a psychotropic drug and antidepressant <2004CHE507>. 

Many clinically available drugs that modify sleep-wake cycles and appetite act through the histaminergic system. Blockade of brain H receptors induces drowsiness and other signs of central nervous system depression... 

Herbai sedatives and anxioiytics are a diverse group of plant drugs that commonly act as depressants of the central nervous system (CNS) (table 6.1). Pharmaceutical CNS depressants are used as anxiolytics, anti-epiieptics, sedatives, sleep-inducers (sedatives or hypnotics), general anesthetics, and recreationai drugs (e.g., ethanol) (table 6.2). CNS... 

Catecholamines, 6 (1969) 200 Cell membrane transfer, 14(1977) 1 Central nervous system, drugs, transmitters and peptides, 23 (1986) 91 Centrally acting dopamine D2 receptor agonists, 29 (1992) 185 Chartreusin, 19 (1982) 249 Chelating agents, 20 (1983) 225... 

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