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Cellular retinol-binding protein levels

Within the enterocyte, retinol is bound to cellular retinol binding protein (CRBP 11) and is esterified by lecithin retinol acyltransferase (LRAT), which uses phosphatidylcholine as the fatty acid donor, mainly yielding retinyl palmitate, although small amounts of stearate and oleate are also formed. At unphysiologically high levels of retinol, when CRBP 11 is saturated, acyl coenzyme A (CoA) retinol acyltransferase (ARAT) esterifies the free retinol that accumulates in intracellular membranes. Then the retinyl esters enter the lymphatic circulation and then the bloodstream (in chylomicrons), together with dietary lipid and carotenoids (Norum et al., 1986 Olson, 1986 Blomhoff et al., 1991 Green et al., 1993 Harrison and Hussain, 2001). [Pg.36]

Figure L Effects of dietary fats on the levels of -carotene dioxygenase activity and cellular retinol binding protein type II in rat intestinal mucosa. (Adapted with permission from reference 22. Copyright 1998 The American Society for... Figure L Effects of dietary fats on the levels of -carotene dioxygenase activity and cellular retinol binding protein type II in rat intestinal mucosa. (Adapted with permission from reference 22. Copyright 1998 The American Society for...
Haq RU, Chytil F (1988) Retinoic acid rapidly induces lung cellular retinol-binding protein mRNA levels in retinol deficient rats. Biochem Biophys Res Commun 156 712-716... [Pg.27]

Fisher GJ, Reddy AP, Datta SC, Kang S, Yi JY, Chambon P, Voorhees JJ (1995) A -trans retinoic acid and diW-trans retinol induce cellular retinol-binding protein in human skin in vivo. J Invest Dermatol 105 80-86 Kang S, Duell EA, Fisher GJ, Datta SC, Wang ZQ, Reddy AP, Tavakkol A, Yi JY, Griffiths CEM, Elder JT et al (1995) Application of retinol to human skin in vivo induces epidermal hyperplasia and cellular retinoid binding proteins characteristic of retinoic acid but without measurable retinoic acid levels or irritation. J Invest Dermatol 105 549-556... [Pg.157]

Kang S, Duell EA, Fisher GJ, et al (1995) Application of retinol to human skin in vivo induces epidermal hyperplasia and cellular retinoid binding proteins characteristic of retinoic acid but without measurable retinoic acid levels or irritation. J Invest Dermatol 105 549-556... [Pg.174]

See other pages where Cellular retinol-binding protein levels is mentioned: [Pg.36]    [Pg.36]    [Pg.32]    [Pg.349]    [Pg.276]    [Pg.322]    [Pg.325]    [Pg.113]    [Pg.699]    [Pg.189]    [Pg.334]    [Pg.172]    [Pg.91]    [Pg.228]   
See also in sourсe #XX -- [ Pg.110 , Pg.114 , Pg.115 ]



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