Cationic conjugated polyelectrolyte

Woo F1Y, Vak D, Korystov D, Mikhailovsky A, Bazan GC, Kim DY (2007) Cationic conjugated polyelectrolytes with molecular spacers for efficient fluorescence energy transfer to dye-labeled DNA. Adv Funct Mater 17 290-295... 

Liu B, Bazan GC (2007) Tetrahydrofuran activates fluorescence resonant energy transfer from a cationic conjugated polyelectrolyte to fluorescein-labeled DNA in aqueous media. Chem Asian J 2 499-504... 

Wang and co-workers [46] studied the interactions of PPE-based cationic conjugated polyelectrolytes (CPE) and OPE using Escherichia coli cells to gain an understanding of the dissimilarities in the killing mechanisms between CPE and OPE in dark... 

Xing C, Yu M et al (2(X)7) Fluorescence tum-on detection of nitric oxide in aqueous solution using cationic conjugated polyelectrolytes. Macromol Rapid Commun 28 241-245... 

FIGURE 13.3 Schematic presentation of a detection scheme for DNA hybridization, utilizing quenching of a cationic conjugated polyelectrolyte by a fluorophore-labeled PNA probe. 

Microspheres coated with streptavidin and biotinylated anionic-conjugated electrolytes are presented to a quencher-labeled biotinylated peptide substrate. Quenching of the fluorescence from the conjugated polyelectrolyte occurs as the peptide binds to the microsphere. The quencher is removed when the peptide is cleaved by the protease, detected as enhancement of the fluorescence from the conjugated polyelectrolyte. The assay can also be used with a cationic-conjugated polyelectrolyte and solution sensors based on a polyelectrolyte--avidin ensemble were also reported [49], These... 

FIGURE 13.11 Schematic description of the specific detection of a-thrombin by use of a ssDNA aptamer (black line) and a cationic-conjugated polyelectrolyte (black dotted line). (From Ho, H.A., and Leclerc, M., /. Am. Chem. Soc., 126, 1384, 2004.)... 

Davies ML, Douglas P, Burrows HD et al (2011) Effect of aggregation on the photophysical properties of three fluorene-phenylene-based cationic conjugated polyelectrolytes. J Phys Chem B 115 6885-6892... 

Similar assays for measuring protease activity were also reported by Whitten and coworkers [49], These assays utilize polystyrene microspheres that are coated with streptavidin (a biotin-binding protein) and a biotinylated anionic fluorescent conjugated polyelectrolyte or a cationic polyelectrolyte, A biotinylated quencher-labeled peptide serves as a substrate for the enzyme and when mixed with the microspheres, a strong complex similar to the one in the DNA assays described in Section 13,3,1, through the biotin-avidin interaction is created [49], A schematic drawing of the assay is shown in Figure 13,7,... 

Davies ML, Burrows HD, Moran MC et al (2009) Cationic fluorene-based conjugated polyelectrolytes induce compaction and bridging in DNA. Biomacromolecules... 

Henson ZB, Zhang Y, Nguyen T-Q, Seo JH, Bazan GC (2013) Synthesis and properties of two cationic narrow band Gap conjugated polyelectrolytes. J Am Chem Soc 135 4163-4166... 

Schanze et al. have described the layer-by-layer (LBL) fabrication of multilayer films and photovoltaic cells using poly(phenylene ethynylene)-based anionic conjugated polyelectrolytes as electron donors and water-soluble cationic fuUerene C ) derivatives as acceptors [44]. LBL film deposition was found to be linearly related to the number of bUayers, as monitored by UV/vis absorption. Atomic force microscopy (AFM) and scanning electron microscopy (SEM) of the mtiltilayer... 

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