Carrier, biochemical engineering

Kirdponpattara S. and Phisalaphong M. Bacterial cellulose-alginate composite sponge as a yeast cell carrier for ethanol production. Biochemical Engineering Journal 77 (2013) 103-109. 

The rapid development of biotechnology during the 1980s provided new opportunities for the application of reaction engineering principles. In biochemical systems, reactions are catalyzed by enzymes. These biocatalysts may be dispersed in an aqueous phase or in a reverse micelle, supported on a polymeric carrier, or contained within whole cells. The reactors used are most often stirred tanks, bubble columns, or hollow fibers. If the kinetics for the enzymatic process is known, then the effects of reaction conditions and mass transfer phenomena can be analyzed quite successfully using classical reactor models. Where living cells are present, the growth of the cell mass as well as the kinetics of the desired reaction must be modeled [16, 17]. 

This volume contains most of the papers presented at the symposium. In addition, several chapters written by leading experts in the field have also been included. Several important aspects of immobilized microbial cell technology are discussed here carriers for immobilization, methods of cell attachment, biophysical and biochemical properties, reactor design, and process engineering of bound cell systems. A number of applications in the food, pharmaceutical, and medical areas— including those commercialized already— have been described. In essence, this is a comprehensive single volume state-of-the-art presentation of immobilized microbial cell systems. 

H. et al. (2009) Technical strategies to improve tissue engineering of cartilage-carrier-constructs. Adv. Biochem. Eng. Biotechnol, 112, 145-181. 

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