Cardizem - Diltiazem hydrochloride

Diltiazem Hydrochloride Cardizem SR 60, 90, 120 mg extended-release capsirles... [Pg.99]

DUtlazem Hydrochloride. Diltiazem hydrochloride, (-t-)-c s-3-(acetoxy)-5- 2(dimcthylamino)ethyl -2.3-dihydro-2-(4-mc(hoxyphenyl)l. S-benzo(hia/.epin-4(Sf/)onc hydrochloride (Cardizem). was developed and introduced in Japan as a cardiovascular agent to treat angina pectoris. It was observed to dilate peripheral arteries and arterioles. The drug increases myocardial oxygen supply by relieving coronary... [Pg.630]

Example Diltiazem hydrochloride (Cardizem) Route PO/IV Pregnancy Pharmacokinetic Well category C absorbed from GI tract. PB 70%-80% Undergoes first-pass metabolism in liver. Metabolized in liver excreted in urine not removed by hemodialysis... [Pg.292]

Diltiazem hydrochloride has principal tradenames of Dilacor and Cardizem . It has also been known as CRD-401, RG 83606, Altiazem , Anginyl , Angize , Britiazi , Bruzen , Calcicard , Cardiem , Dilpral , Dilzem , Dilzene , Herbesser , Masdii and Tildiem . Diltiazem hydrochloride possesses two asymmetric carbons and is supplied as the dextrorotatory cis-isomer. Diltiazem, when referenced, indicates the free base (CAS registry number 42399-41-7). [Pg.57]

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