Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Cardiac channel

Interactions with the hERG cardiac channel leading to QT interval prolongation (e.g., some antipsychotics and antihistamines drugs)... [Pg.246]

Nifedipine (a dihydropyridine) Block of vascular L-type calcium channels > cardiac channels Like verapamil and diltiazem less cardiac effect Prophylaxis of angina, hypertension Oral, duration 4-6 h Toxicity Excessive hypotension Interactions Additive with other vasodilators... [Pg.267]

Expectations from In silico Models for Cardiac Channel Safety Pharmacology 558... [Pg.545]

Availability of Gold Standard Databases for Cardiac Channel SAR 558... [Pg.546]

Global SAR or Rule-Based Models for Safety Pharmacology for Cardiac Channels 559... [Pg.546]

Local SAR Rule and Descriptor-Based Models in Cardiac Channel Safety Pharmacology 560... [Pg.546]

Pearlstein R, Vaz R, Rampe D. Understanding the structure-activity relationship of the human ether-a-go-go-related gene cardiac channel. A model for bad behavior. J Med Chem 2003 46 2017-2022. [Pg.1555]

Long QT syndrome 3 SCN5A (cardiac channel) 1505-1507 Deletion of KQP and length of cardiac causing Prolonged opening action potential, persistent current... [Pg.169]

Zhou J, AugeUi-Szafran CE, Bradley JA et al (2005) Novel potent human ether-a-go-go-related (hERG) cardiac channel enhancers and their in vitro antiarrhythmic activity. Mol Pharmacol 68 876-884... [Pg.66]

Explraatray Safety Pharmacology Studies with Cardiac Channels Involved in Cardiac... [Pg.47]

See other pages where Cardiac channel is mentioned: [Pg.321]    [Pg.329]    [Pg.330]    [Pg.51]    [Pg.51]    [Pg.395]    [Pg.308]    [Pg.309]    [Pg.309]    [Pg.310]    [Pg.311]    [Pg.158]    [Pg.194]    [Pg.545]    [Pg.545]    [Pg.556]    [Pg.558]    [Pg.409]    [Pg.1534]    [Pg.136]    [Pg.82]    [Pg.134]    [Pg.60]    [Pg.184]    [Pg.185]    [Pg.53]    [Pg.169]    [Pg.178]    [Pg.179]    [Pg.238]    [Pg.85]   
See also in sourсe #XX -- [ Pg.556 , Pg.558 ]



SEARCH



Calcium channel blocker cardiac effects

Calcium channel blockers cardiac glycosides

Calcium channels cardiac

Cardiac circulatory medications calcium channel blockers

Cardiac drugs calcium channel blockers

Cardiac ion channels

Human cardiac sodium channel

Pharmacogenetics and Cardiac Ion Channels

Potassium channels cardiac

Potassium channels cardiac tissue

Sodium channels cardiac

© 2024 chempedia.info