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Carboxylic 3,5-dihydroxy

Ethers of benzenepentol have been obtained by Dakin oxidation of the appropriately substituted acetophenone. Thus, the oxidation of 2-hydroxy-3,4,6-ttimethoxyacetophenone and 2-hydroxy-3,4,5-ttimethoxyacetophenone with hydrogen peroxide ia the presence of alkali gives l,2-dihydroxy-3,4,6-ttimethoxybenzene and l,2-dihydroxy-3,4,5-ttimethoxybenzene, respectively further methylation of these ethers yields the pentamethyl ether of benzenepentol (mp 58—59 degC) (253). The one-step aromatization of myoinositol to produce esters of pentahydroxybenzene is achieved by treatment with carboxylic acid anhydrides ia DMSO and ia the presence of pyridine (254) (see Vitamins). 6-Alkyl- or... [Pg.389]

Aluminum salts of carboxylic acids, aluminum carboxylates, may occur as aluminum tricarboxylates (normal aluminum carboxylates), Al(OOCR)2 monohydroxy (monobasic) aluminum dicarboxylates, (RCOO)2Al(OH) and dihydroxy (dibasic) aluminum monocarboxylates, RCOOAl(OH)2. Aluminum carboxylates are used in three general areas textiles, gelling, and pharmaceuticals. Derivatives of low molecular weight carboxyUc acids have been mainly associated with textile appHcations those of fatty carboxyUc acids are associated with gelling salts and more complex carboxylates find appHcations in pharmaceuticals. [Pg.142]

Benzo[b]thiophene-2-carboxylic acid, 4,7-dihydroxy-synthesis, 4, 928... [Pg.561]

In a second synthesis the same authors start with ethyl 2 4-dihydroxy-6-methylpyridine-3-carboxylate, and by a shorter series of reactions reach 3-cyano-2 4-dimethoxypyridine (V), which is then converted into rieinine (VI) as before. [Pg.7]

The tri/luorovinyloxy group is cleaved by potassium persulfate [37J The pnmanly formed dihydroxy compound undergoes spontaneous hydrolysis with the formation of carboxylic acid (equation 29)... [Pg.331]

ZN(C)153, 00ZN(C)323, 00ZN(C)857, 01MI2, 01MIP4, 01TL5849). 5-Amino-8,9-dihydroxy-2,3-dihydro-l//-pyrimido[l,2-u]quinoline-3-carboxylic acid moiety 4 was also identified as a chromophoric moiety of certain... [Pg.265]

Hydrogenolytic cleavage of isoxazolines has also proved useful in preparation of -dihydroxy ketones and -hydroxy carboxylic acids (47). The isoxazolines were prepared by a [3 -1- 2] cycloaddition. [Pg.141]

Chemical Name 7-chloro-2,3-dihydro-2,2-dihydroxy-5-phenyl-1 H-1,4-benzodiazepine-3-carboxylic acid dipotassium salt... [Pg.377]

It was anticipated that fragments 147 and 214 could be united through an amide bond linking the nitrogen atom of the latter with C-8 of the former. Indeed, the active ester formed by treatment of carboxylic acid 147 with 1,3-diisopropylcarbodiimide and 1-hydro-xybenzotriazole reacts efficiently with amine 214 to afford dihydroxy amide 215 in 95 % yield. This convergent union creates a molecule that possesses all but two carbon atoms of the natural product. [Pg.624]

Various nucleophiles undergo addition to oxepins to give functionalized cyclohexadienols. Thus, terf-butyl oxepin-4-carboxylate when treated with a methanolic solution of lithium hydroxide gives /ert-butyl ow .v-5-hydroxy-6-methoxycyclohexa-l,3-diene-1-carboxylate (3a) in 56% yield.156 When dioxane is used as solvent, the respective dihydroxy derivative 3b is obtained in 30 % yield. Sodium azide reacts with oxepin to give mws-6-azidocyclohexa-2,4-dien-l-ol (3c) in 55% yield.212... [Pg.46]

Polyesters. The polycondensation prods of di-carboxylic acids with dihydroxy alcohols. [Pg.812]

The pendant hydroxy groups of ethylene oxide-propylene oxide copolymers of dihydroxy and trihydroxy alcohols may be sulfurized to obtain a sulfurized alcohol additive. This is effective as a lubricant in combination with oils and fats [387,533]. The sulfurized alcohols may be obtained by the reaction of sulfur with an unsaturated alcohol. Furthermore, fatty alcohols and their mixtures with carboxylic acid esters as lubricant components [1286] have been proposed. [Pg.14]

The highly ordered cyclic TS of the D-A reaction permits design of diastereo-or enantioselective reactions. (See Section 2.4 of Part A to review the principles of diastereoselectivity and enantioselectivity.) One way to achieve this is to install a chiral auxiliary.80 The cycloaddition proceeds to give two diastereomeric products that can be separated and purified. Because of the lower temperature required and the greater stereoselectivity observed in Lewis acid-catalyzed reactions, the best diastereoselectivity is observed in catalyzed reactions. Several chiral auxiliaries that are capable of high levels of diastereoselectivity have been developed. Chiral esters and amides of acrylic acid are particularly useful because the auxiliary can be recovered by hydrolysis of the purified adduct to give the enantiomerically pure carboxylic acid. Early examples involved acryloyl esters of chiral alcohols, including lactates and mandelates. Esters of the lactone of 2,4-dihydroxy-3,3-dimethylbutanoic acid (pantolactone) have also proven useful. [Pg.499]

Displacement of the 3-hydroxyl group of 74 was carried out with Et2NSF3 (DAST) (DAST - diethylaminosulfur trifluoride) in dichloromethane. The expected fluorinated product 75 on treatment with aqueous perchloric acid led to regioselective epoxide ring opening to give 76, which on treatment with hydrazine hydrate at 100 °C for 18 h yielded 3,4-dihydroxy-8-oxo-octahydropyridazino[l,6-r/][l,2,4]triazine-l-carboxylic acid phenylamide 77 (Scheme 3) <1997T9357>. [Pg.336]

The reaction of 5-amino-2-hydroxypyridine and EMME refluxing diphenyl ether for 1 hr gave 4,6-dihydroxy-1,5-naphthyridine-3-carboxylate in 20% yield after vacuum sublimation of the crude product (71JOC1331). [Pg.212]


See other pages where Carboxylic 3,5-dihydroxy is mentioned: [Pg.317]    [Pg.277]    [Pg.753]    [Pg.568]    [Pg.438]    [Pg.446]    [Pg.176]    [Pg.265]    [Pg.607]    [Pg.693]    [Pg.90]    [Pg.2353]    [Pg.37]    [Pg.186]    [Pg.400]    [Pg.407]    [Pg.531]    [Pg.531]    [Pg.202]    [Pg.128]    [Pg.128]    [Pg.168]    [Pg.193]    [Pg.197]    [Pg.197]    [Pg.15]    [Pg.191]    [Pg.147]    [Pg.225]    [Pg.210]   
See also in sourсe #XX -- [ Pg.128 ]




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3.4- dihydroxy carboxylic acid

Carboxylic acid amid 4,5-dihydroxy

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