Amides to Carboxylic Acids

Amination of Free Carboxylic Acids to Amides and Imides... 

Bile acids can be modified to many derivatives due to their unique molecular structures, as listed in Table 1. First, we can convert the functional groups at the side-chains from carboxylic acid to amide, alcohol, ester, and so on. Second, we can change the length of the side-chains by decreasing or increasing their methylene number. Third, we can regulate the direction of the hydroxyl groups of the skeletons at the axial or equatorial positions. 

Single-step conversion of carboxylic acids to amides has been achieved using the A -PSP/BusP reaction system in the presence of amines (equation 17). ... 

Conversion by means of NH3 of carboxylic acids to amides, of aldehydes into nitriles or of ketones into tetrazoles or amides (see 1st edition). 

Mechanism 22.7 Conversion of Carboxylic Acids to Amides with DCC Part [1] Conversion of OH into a better leaving group... 

Fischer Esterification—Acid-Catalyzed Conversion of Carboxylic Acids to Esters 848 Conversion of Carboxylic Acids to Amides with DCC 850 Acid-Catalyzed Hydrolysis of an Ester to a Carboxyhc Acid 851 Base-Promoted Hydrolysis of an Ester to a Carboxyhc Acid 852 Amide Hydrolysis in Base 856 Hydrolysis of a Nitrile in Base 864 Reduction of a Nitrile with LiAlH4 865 Reduction of a Nitrile with DIBAL-H 866... 

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