2- Carboxy-3,6-dihydroxy-4-

CH3 4-Anilino-2-carboxy-3,6-dihydroxy-4 -methyl-... 75 181-182 4-Anilino-2,5-dihydroxy-4 -methyl-... 75 185... 

CH3 H 2-Carboxy-3,6-dihydroxy-4-(2-methyl-anilino)-... 93 177-178 2,5-Dihydroxy-4-( 2-methyl-anilino )-... 93 183... 

Most xanthene dyes are classified as basic dyes by their method of appHcation acid dyes can be produced by introduction of sulfonic acid groups. The fluoresceins, which contain carboxy and hydroxy substituents, are also acid dyes for coloration of silk. Some of the fluoresceins in which the carboxy group has been esterified, are soluble in alcohol or other organic solvents and can be classified as solvent dyes. Mordant dyes can be produced by introducing o-dihydroxy or sahcyhc acid groups (2), which when metallised can have very good lightfastness. 

Kinetic studies on the bulk polyesterification of a,o-dicarboxy poly(hexamethylene adipate) with a,polymeric medium. Solomon s mechanism1 can be considered as reasonable. 

Only a few building blocks are available for the synthesis of ester-containing rigid mesogenic units, namely dihydroxy-, dicarboxy-, or (hydroxy, carboxy)-l,4-phenylenes, 4,4,-biphenylenes, and 2,6-, 1,4-, or 1,5-naphthylenes (Table 2.15). 

Benzyloxy-3-oxo-1 -(formyl-methyl)- 495 exo-4, exo-9-Dihydroxy-exo-l-methyl-endo-5-(2-carboxy-athyl)-trans- 312... 

Dihydroxy-9-oxo-6,10-dimethyl-3-( 1-carboxy-athyl)- - 2,3 -lacton 517 4-Hydroxy-9-oxo-6,10-dimethyl-3-( 1 -carboxy-athyl)- -4,3 -lacton 517... 

Dihydroxy-16a-carboxy- 157 3/3,21 -Dihydroxy-16a, 17a-epoxy- 779 3,20-Dioxo-16 -carboxy- 157 3/3-Hydroxy-16a-acetoxy-20-oxo- 514 17a-Hydroxy-3/ ,21-diacetoxy-20-oxo- 778 3/3-Hydroxy-16a, 17a -epoxy-20-oxo- 779... 

If the polyester synthesis is performed with equimolar amounts of diol and diacid, then, in addition to hydroxy, carboxy-terminated oligomers, dihydroxy- and dicarboxy-terminated oligomers are formed, as shown below. In a thermodynamic equilibrium, the molar ratios of the three functionality fractions should be 2 1 1, respectively. 

Schwarz et al. in agreement with Shukla observed the formation of 2-Oxo-l, 2-dihydroquinoline, 8-hydroxy-2-oxo-l, 2-dihydroquinoline, 8-hydroxycoumarin, and 2,3-dihydroxy-phenylpropionic acid were found as intermediates of quinoline transformation by P. fluorescens 3 and P. putida 86 [325], They compared that metabolic pathway with the one obtained for Rhodococcus strain B1 (Fig. 22). This bacterium was unable to yield denitrogenated metabolites (i.e., 2-oxo-l, 2-dihydroquinoline, 6-hydroxy-2-oxo-l, 2-dihydroquinoline, and 5-hydroxy-6-(3-carboxy-3-oxopropenyl)-lH-2-pyridone). 

To have sufficient stability for commercial application, chelating tridentate azo ligands (5) are required.7 The most important and widely used tridentate azo ligands are the ortho,ortho -dihydroxy azo dyes, i.e., (5, X = Y = OH). Other tridentate azo ligands are ortho-carboxy-ortho -hydroxyazo and or tho-hydvoxy-ort ho - Ammo zo. 

Estrone, or l,17p-Dihydroxy-4-methylestra-1,3,5(10)triene 3-(l-Oxo-8p-methyl-5p-carboxy-trans-perhydroindanyl-4 a)propionic acid C [248]... 

Cl 4-Anilino-2-carboxy-4 -chlor-3,6-dihydroxy-... 86 203 4- Anilino-4 -chlor-2,5-di-hydroxy-. .. 89 203... 

Metabolism is the major route of elimination of THC from the body as little is excreted unchanged. In humans, over 20 metabolites have been identified in urine and feces 26 Metabolism in humans involves allylic oxidation, epoxidation, aliphatic oxidation, decarboxylation, and conjugation. The two monohydroxy metabolites (Figure 4.7) 11-hydroxy (OH)-THC and 8-beta-hydroxy THC are active, with the former exhibiting similar activity and disposition to THC, while the latter is less potent. Plasma concentrations of 11-OH-THC are typically <10% of the THC concentration after marijuana smoking. Two additional hydroxy compounds have been identified, namely, 8-alpha-hydroxy-THC and 8,11-dihydroxy-THC, and are believed to be devoid of THC-like activity. Oxidation of 11-OH-THC produces the inactive metabolite, ll-nor-9-carboxy-THC, or THC-COOH. This metabolite may be conjugated with glucuronic acid and is excreted in substantial amounts in the urine. 

Dihydroxy-2-carboxy benzoyl methyl ketone (VI) Acetic acid 3,5-Dihydroxyphthalic acid (VII) - 4... 

C 7I11204 3468-01-7) see F lavoxate 7a-carboxymethylpyrrolizine (C,jH, N02 94794-30-6) see Pilsicainide 17p-carboxy-5-oxo-A-nor-3,5-secoandrostan-3-oic acid (C <,I12k05 76763-14-9) see Finasteride (HP)-21-(3-carboxy-l-oxopropoxy)-ll,17-dihydroxy-pregna-1,4-diene-3,20-dione... 

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