2-Formyl-l-methyl

In addition to examining the vinylation of l-methyl-2-indolecarboxaldehyde with methyl acrylate (Pd(OAc>2/HOAc/AgOAc) to give methyl ( )-3-(2-formyl-l-methyl-3-indoiyl)-acrylate in 60% yield, Pindur found that similar reactions of methyl 3-(l-methyl-2-indolyl)-acrylate afford bis(carbomethoxy)carbazoles albeit in low yield [85]. Fujiwara discovered that the combination of catalytic Pd(OAc)2 with benzoquinone and t-butylhydroperoxide serves to couple indole with methyl acrylate to give methyl ( )-3-(3-indolyl)acrylate in 52% yield [86]. 

Kaiser, S.C. 1959. Metabolism of 2-formyl-l-methyl pyrldlnlum Iodide oxime (2-PAM). CWLR 2347. 

Chlor-3,3-diphenyl-2-formyl-l-methyl-2,3-dihydro-indol 35%... 

Amino-4-methylpyrimidine 2-Formyl-l-methyl-5-nitroimidazole Sulfuric acid... 

Into a mixture of 1.6 g of 2-amino-4-methylpyrimidine with 10 ml of glacial acetic acid is slowly added 2.13 g of concentrated sulfuric acid. A mixture of 2.4 g of 2-formyl-l-methyl-5-nitroimidazole in 20 ml of glacial acetic acid is slowly added to the mixture of the pyrimidine under stirring. The reaction... 

H-Azirin 2-Aminocarbonyl-3-phenyl- IV/5a, 565 Benzimidazol 2-Formyl-l-methyl-IV/la, 347... 

Dimethyl-2-formyl-l-methoxycar-bonyl- 85, 1074, 1774, 1779, 1885 1 -Ethoxycarbonyl-2-formyl-l -methyl-101... 

Imidazole, 4-formyl-5-hydroxy-l-phenyl-mesoionic, 5, 372 Imidazole, 2-formyl-1-methyl-mass spectra, S, 360 Imidazole, 2-formyl-l,4,5-trimethyl-... 

Pyrrole, 2-aeetyl-l-(2-hydroxyethyl)-5-nitro-cyelization, 4, 74 ipso substitution, 4, 243 Pyrrole, 2-aeetyl-l-methyl-dipole moment, 4, 194 photocyelization reaetions with 2,3-dimethylbut-2-ene, 4, 269 Pyrrole, 3-acetyl-4-methyl-Vilsmeier-Haaek formylation, 4, 222 Pyrrole, 2-aeetyl-3-nitro-reduction, 4, 297 Pyrrole, aeyl-basicity, 4, 207 isomerization, 4, 208 oximes... 

Ethyl 10-chloro-7-methyl-6-oxo-l lb-phenyl-5,6,7,1 lb-tetrahydroisoxazolo[2, 3- /][l,4]benzodiazepine-l-carboxylate (563) gave a separable mixture of 6-chloro-4-(2-ethoxycarbonyl-2-formyl-l-phenylvinyl)-l-methyl-3,4-dihy-dro-2(17/)-quinoxalinone (564), 4-(2-benzoyl-2-ethoxycarbonylvinyl)-6-chloro-1-methyl-3,4-dihydro-2(l//)-quinoxalinone (565), and 6-chloro-l-methyl-3,4-dihydro-2(l//)-quinoxalinone (567) (EtOH, reflux, 21 h 2%, 8%, and 20%, respectively, after separation structures 564 and 565 were... 

Other Methods of Preparation.—Ethyl 2-formyl-5-methyl-4-furoate has also been prepared by the oxidation of ethyl 2-(D-ara6ino-tetrahydroxybutyl)-5-methyl-4-furoate by means of periodic acid,8 sodium periodate,19 or minium ( red lead ) in acetic acid.66 It can also be prepared by the oxidation with sodium periodate of ethyl 2-(D-lyzo-tetrahydroxybutyl)-5-methyl-4-furoate,15 of ethyl 2-(D-fftreo-trihydroxy-propyl)-5-methyl-4-furoate,13 of ethyl 2-(o-erythro-trihydroxypropyl)-5-methyl-4-furoate,17 of ethyl 2-(L-eryfAro-trihydroxypropyl)-5-methyl-4-furoate,13 and of ethyl 2-(D-goIado-pentahydroxypentyl)-5-methyl-4-furoate.16... 

Dimethylcyclohexanone and 2-benzyl-2-methylcyclohex-anone have been prepared similarly in yields of 60% and 55%, respectively.2 The procedure has been extended to the synthesis of 9-methyl-, 9-w-butyl-, and 9-benzyl-l-decalone from the dianion of 2-formyl-l-decalone in yields of 55%, 48%, and 58%, respectively.2... 

Das Gupta, S., Moorthy, M.V., Chowdhri, B.L. and Ghosh, A.K. Effect of thiamine hydrochloride on the blood level of 2-formyl 1-methyl pyridinium oxime chloride (2-PAM.Cl) in rats. 

Die durch Fluorid-Ionen induzierte Cyclisierung von Dichlor-essigsaure-[N-(2-trimethylsilyl-oximino-propyl)-anilid] fiihrt direkt zu 2-Formyl-4-methyl-l-phenyl-imidazol-3-oxidni. Die eigentlich erwartete 2-Dichlormethyl-Verbindung konnte nicht isoliert werden. 

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