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Carbonyl compounds acid derivatives reactions with organometallic reagents

The carbonyl group of acid derivatives reacts with the nucleophilic carbanion available from organo-metallic reagents. However, the reactions of the individual classes of compounds are not as straightforward as the addition reactions of organometallic compounds with aldehydes and ketones. Addition of a carbanion to the acyl carbon atom generates a tetrahedral intermediate that can decompose to give a ketone that will react further with another equivalent of the carbanion. [Pg.724]

The reactions of several carboxylic acid derivatives with organomagnesium and organolithium compounds were described in Section 14-12. The key step in these reactions is addition of the organometallic compound, as R60MS , to the carbonyl group. For a Grignard reagent,... [Pg.823]


See other pages where Carbonyl compounds acid derivatives reactions with organometallic reagents is mentioned: [Pg.134]    [Pg.467]    [Pg.79]    [Pg.571]    [Pg.200]    [Pg.571]    [Pg.315]    [Pg.65]    [Pg.105]    [Pg.620]    [Pg.328]    [Pg.1453]    [Pg.43]    [Pg.3]    [Pg.5235]    [Pg.330]    [Pg.141]    [Pg.677]    [Pg.141]    [Pg.20]    [Pg.72]    [Pg.436]    [Pg.149]    [Pg.1210]    [Pg.90]    [Pg.309]    [Pg.180]    [Pg.301]    [Pg.176]    [Pg.141]    [Pg.677]    [Pg.132]    [Pg.383]    [Pg.260]    [Pg.271]    [Pg.289]    [Pg.59]    [Pg.619]    [Pg.4]    [Pg.140]   
See also in sourсe #XX -- [ Pg.612 ]




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Acid Reagents

Acidic carbonyl

Acidic compounds, reaction

Acidic reagents

Acids reaction with organometallic compounds

Acids, acid with organometallics

Carbonyl compound derivatives

Carbonyl compounds organometallic reagents

Carbonyl compounds reactions with organometallic reagents

Carbonyl compounds reagents

Carbonyl compounds, reactions

Carbonyl derivatives

Carbonyl reagent

Carbonylation derivatives

Organometallic acidity

Organometallic compounds carbonyls

Organometallic compounds reaction

Organometallic compounds with

Organometallic compounds with acid derivatives

Organometallic derivative

Organometallic reagents

Organometallic reagents compounds

Organometallic reagents derivatives

Reaction with carbonyl compounds

Reaction with organometallic reagents

Reaction with organometallics

Reactions with Carbonyl Derivatives

Reactions with organometallic compounds

With Carbonyl Compounds

With carbonyl derivatives

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