Hypertension carbamazepine

Because bupropion is metabolized in the liver, medications that alter hepatic enzyme metabolism, such as carbamazepine or cimetidine, may effect blood concentrations. Bupropion should not be administered in combination with the MAOIs because of risk of hypertensive crisis. Levo-dopa use in conjunction with bupropion has been associated with confusion, hallucinations, and dyskinesia. Although generally well tolerated, there are case reports documenting that the... 

A 58-year-old woman with a history of hypertension and mental illness (manic depression and schizophrenia) was found dead in bed, with white foam around her mouth. Zolpidem and carbamazepine were found in her urine. 

There has been a report of carbamazepine-induced hypertension (6). 

Jette N, Veregin T, Guberman A. Carbamazepine-induced hypertension. Neurology 2002 59(2) 275-6. 

The major receptor-mediated adverse effect is water intoxication, which can occur with desmopressin or vasopressin. Many drugs, including carbamazepine, chlorpropamide, morphine, tricyclic antidepressants and NSAIDs, can potentiate the antidiuretic effects of these peptides, while lithium, demeclocycline and ethanol can attenuate the antidiuretic response to desmopressin. Desmopressin and vasopressin should be used cautiously when a rapid increase in extracellular water may impose risks (e.g., in angina, hypertension, and heart failure) and should not be used in patients with acute renal failure. Patients receiving desmopressin to maintain hemostasis should be... 

Nervous system Drug-resistant hypertension with leukoencephalopathy might have been due to carbamazepine [76 ]. 

A 21-year-old man who took carbamazepine for idiopathic trigeminal neuralgia for several days developed arterial hypertension (from 110/60 to 170/126 mmHg) followed by disturbance of consciousness. An MRI scan showed transient hyperintense lesions in the bilateral fronto-parieto-occipital subcortical white matter, suggesting the presence of vasogenic edema caused by hypertension. Despite the administration of various antihypertensive... 

Furuta N, Fujita Y, Sekine A, Ikeda M, Okamoto K. Reversible posterior leukoen-cephalopathy syndrome associated with carbamazepine-induced hypertension. Rin-sho Shinkeigaku 2009 49(4) 191-3. 

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