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Capsule-filling machines

Table 2 Selected Automatic Capsule-Filling Machines... Table 2 Selected Automatic Capsule-Filling Machines...
Fig. 9 Hofliger Karg model GKF 1500 automatic capsule-filling machine. (Courtesy of Robert Bosch Corp., Packaging Machinery Division, South Plainfield, NJ.)... [Pg.351]

Modern automatic capsule-filling machines offer enormous flexibility in terms of what can be filled into... [Pg.356]

E. Instrumentation of Capsule-Filling Machines and Their Role in Formulation Development... [Pg.356]

Fig. 16 Typical force-time trace from an instrumented Zanasi LZ-64 automatic capsule-filling machine. PC, precompression resulting from dipping of dosator into the powder bed C, compression resulting from actual piston tamping R, retention force Ej, ejection D, drag force developing during retraction of piston. (From Ref. 38.)... Fig. 16 Typical force-time trace from an instrumented Zanasi LZ-64 automatic capsule-filling machine. PC, precompression resulting from dipping of dosator into the powder bed C, compression resulting from actual piston tamping R, retention force Ej, ejection D, drag force developing during retraction of piston. (From Ref. 38.)...
Fig. 17 Effect of powder bed height, piston height, and compression force on plug ejection force in an instrumented Zanasi LZ-64 automatic capsule-filling machine (pregelatinized starch lubricated with 0.005% magnesium stearate). Note that the first point of each curve is precompression. Piston height (mm) , 15 -jlf, 14 , 13 , 12. Powder bed height (mm) heavy line, 30 light line, 50. (From Ref. 51.)... Fig. 17 Effect of powder bed height, piston height, and compression force on plug ejection force in an instrumented Zanasi LZ-64 automatic capsule-filling machine (pregelatinized starch lubricated with 0.005% magnesium stearate). Note that the first point of each curve is precompression. Piston height (mm) , 15 -jlf, 14 , 13 , 12. Powder bed height (mm) heavy line, 30 light line, 50. (From Ref. 51.)...
Piezoelectric transducers have also been used to instrument automatic capsule filling machines. Mony et al. [72] instrumented a Zanasi RV/59 by fitting a piezoelectric load cell to the upper end of a piston. This... [Pg.359]

KB Shah, LL Augsburger, LE Small, GP Polli. Instrumentation of a dosing disc automatic capsule filling machine. Pharm Tech 7(4) 42-54, 1983. [Pg.380]

LE Small, LL Augsburger. Instrumentation of an automatic capsule filling machine. J Pharm Sci 66 504— 509, 1977. [Pg.380]

GM Irwin, GJ Dodson, LJ Ravin. Encapsulation of clomacron phosphate I. Effect of fiowability of powder blends, lot-to-lot variability, and concentration of active ingredient on weight variation of capsules filled on an automatic capsule filling machine. J Pharm Sci 59 547-550, 1970. [Pg.380]

K Marshall. Instrumentation of tablet and capsule filling machines. Pharm Tech 7(3) 68-82, 1983. [Pg.380]

LL Augsburger. Instrumented capsule filling machines development and application. Pharm Tech 6(9) 111— 112, 114, 117-119, 1982. [Pg.380]

AM Mehta, LL Augsburger. Simultaneous measurement of force and displacement in an automatic capsule filling machine. Int J Pharm 4 347-351, 1980. [Pg.380]

DJ Rowley, R Hendry, MD Ward, P Timmins. The instrumentation of an automatic capsule filling machine for formulation design studies, paper presented at 3rd International Conference on Powder Technology, Paris, 1983. [Pg.380]

PK Heda, FX Muller, LL Augsburger. Capsule filling machine simulation I Low force compression physics relevant to plug formation. Pharm Devel Tech 4(2) 209-219, 1999. [Pg.381]

P Yeski, M Marvola. Design and use of equipment for simulation of plug formation in hard gelatin capsule filling machines. Acta Pharm Fennica 100 19-25, 1991. [Pg.381]

IG Jolliffe, JM Newton, D Cooper. The design and use of an instrumented mG2 capsule filling machine simulator. J Pharm Pharmacol 34 230-235, 1982. [Pg.381]

JR Britten, MI Barnett. Development and validation of a capsule filling machine simulator. Int J Pharm 71 R5-R8, 1991. [Pg.381]

JR Britten, MI Barnett, NA Armstrong. Studies on powder plug formation using a simulated capsule filling machine. J Pharm Pharmacol 48 249-254, 1996. [Pg.381]

Botzolakis, J.E., Small, L.E., and Augsburger, L.L., Effect of disintegrants on drug dissolution from capsules filled on a dosator-type automatic capsule-filling machine, Int. J. Pharm., 12 341-349 (1982). [Pg.292]

Cropp JW, Augsburger LL, Marshall K. Simultaneous monitoring of tamping force and piston displacement (F-D) on an Hofliger-Karg capsule filling machine. Int J Pharm 1991 71 127-136. [Pg.430]

Britten JR, Barnett MI, Armstrong NA. Construction of an intermittent-motion capsule filling machine simulator. Pharm Res 1995 12 196. [Pg.430]

Guo M, Augsburger LL. Potential application of silicified microcrystalline cellulose in direct-fill formulations for automatic capsule-filling machines. Pharm Dev Technol 2003 8(l) 47-59. [Pg.430]

Small LE, Augsburger LL. Aspects of the lubrication requirements for an automatic capsule-filling machine. Drug Devel Ind Pharm 1978 4 345. Tattawasart A, Armstrong NA. The formation of lactose plugs for hard shell capsules. Pharm Devel Tech 1993 2 335-343. [Pg.431]

Davar N, Shah R, Pope DG, Augsburger LL. Rational approach to the selection of a dosing disk on a Hofliger Karg capsule filling machine. Pharm Tech... [Pg.431]

See other pages where Capsule-filling machines is mentioned: [Pg.340]    [Pg.344]    [Pg.347]    [Pg.348]    [Pg.357]    [Pg.361]    [Pg.361]    [Pg.361]    [Pg.364]    [Pg.372]    [Pg.380]    [Pg.380]    [Pg.420]   


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