Capsular opacification

In the absence of other pathology, the patient s vision should be fully correctable within a few weeks after cataract surgery. Vision that is initially clear after cataract extraction but then deteriorates is suggestive of a postoperative complication, such as capsular opacification, bullous keratopathy, CME, or retinal detachment. 

Topical heparin eyedrops were effective for long-term reduction of fibrotic posterior capsule opacification after extracapsular cataract extraction with intraocular lens implantation (93). Implantation of a heparin drug delivery system into the posterior chamber of experimental animals maintained a significantly higher heparin level in the aqueous humor for a long period of time, suggesting the potential for effective prevention of posterior capsular opacification after phacoemulsification of the lens with no toxic or side effects (94). 

Xie L, Sun J, Yao Z. Heparin drug delivery system for prevention of posterior capsular opacification in rabbit eyes. Graefes Arch Clin Exp Ophthalmol 2003 241 309-313. 

Bacterial adhesion is a serious concern for currently used intraocular lenses (lOLs). Problems lead to a high incidence of endophthalmitis, capsular opacification, and vision activity. MPC has been used in the surface grafting of silicone IOLs and as a coating for acrylic lOLs (see Table 9 in addition, as described earlier in this chapter, they have... 

Plasma treatments have also been applied to intraocular lenses (lOL) to prevent the formation of posterior capsular opacification, e.g. increasing their hydrophilicity and permitting cells to maintain their normal epithelial morphology,or reduce the risk for endophthalimitis, e.g. by coating with poly(2-methacryloyloxyethyl... 

Yuen C, Williams R, Batterbury M, Grierson 1. (2006) Modification of the surface properties of a lens material to influence posterior capsular opacification. Clin Experiment Ophthalmol >A-. 568-574. 

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