Capillary electrochromatography chips

Ceriotti, L., N. F. de Rooij, and E. Verpoorte. An integrated fritless column for on-chip capillary electrochromatography with conventional stationary phases. Anal. Chem. 74, 639-647 (2002). 

Constantin, S., Freitag, R., Solignac, D., Sayah, A., Gijs, M.A.M., Utilization of the sol-gel technique for the development of novel stationary phases for capillary electrochromatography on a chip. Sensors Actuators B 2001, 78, 267-272. 

Finot, M., Jemere, A.B., Oleschuk, R.D., Takahashi, L., Harrison, D.J., High throughput pharmaceutical formulation evaluation and analysis using capillary electrochromatography on a microfluidic chip. Micro Total Analysis Systems, Proceedings 5th lTAS Symposium, Monterey, CA, Oct. 21-25, 2001, 480-482. 

Slentz, B.E., Penner, N.A., Regnier, F.E., Capillary electrochromatography of peptides on microfabricated poly(dimethylsiloxane) chips modified by cerium(IV)-catalyzed polymerization. J. Chromatogr. A 2002, 948, 225-233. 

Bedair, M. and El Rassi, Z., Recent advances in polymeric monohthic stationary phases for electrochromatography in capillaries and chips. Electrophoresis, 25, 4110, 2004. 

Microfluidic chip-based electrochromatography (p-CEC), stemming from capillary electrochromatography (CEC), is a powerful separation technique combining the versatility offered by high-performance liquid chromatography (HPLC) with the high separation efficiency of... 

Wirth et al. [22] prepared a silica colloidal crystal-packed fused-silica capillary column, and 2 cm-long of which was mounted onto a PDMS chip for evaluation of efficiency of capillary electrochromatography. Three fluorophore-labeled proteins, ribonuclease A, cytochrome C, and lysozyme, were well separated over a distance of 1 cm by isocratic electromigration, using acetonitrile/water (40/60) with 0.1 % formic acid. The plate height for lysozyme was... 

Li HF, Zeng HL, Chen ZF, Lin JM (2009) Chip-based enantioselective open-tubular capillary electrochromatography using bovine serum albumin-gold nanoparticle conjugates as the stationary phase. Electrophoresis 30 1022-1029... 

Fig. 3 Open tubular capillary electrochromatography separation on a chip of TRITC-labeled tryptic peptides of P-casein. Source From Two-dimensional electrochromatography/capil-lary electrophoresis on a microchip, in Anal. Chem. ...

Capillary electrochromatography has experienced rapid progress during the last decade, expanding from 17 publications in 1994 to 191 in 2007. This has also led to several books and reviews [93-104] and analytical instrumentation is readily commercially available [105]. The developments in CEC include research on optimum stationary phases (polymer or silica based, adsorbed or imprinted, etc.), mobile phases (aqueous electrolytes with/without admixture of organic solvents or pseudophases) and apparatus design (open-tubular, packed or monolithic capillaries) up to lab-on-a-chip devices for pTAS [107]. 

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