Canolol antimutagenic activities

For example, the main phenol with antioxidative and antimutagenic activities that occurs in crude canola oil is 2,6-dimethoxy-4-vinylphenol known as canolol, which is produced from syringic acids. The major products of caffeic acid pyrolysis at 225 °C are pyrocatechol, 4-vinylpyrocatechol and 4-ethylpyrocatechol (see Section 8.3.4). A more complex mixture of products arises by pyrolysis of lignin, in the smoke condensates used in the meat industry, more than 150 different phenols, and dozens of aromatic alcohols, phenolic acids and hydroxylated heterocyclic compounds have been identified. 

Kuwahara H., Kanazawa A., Wakamatu D., Morimura S., Kida K., Akaike T., Maeda H. Antioxidative and antimutagenic activities of 4-vinyl-2,6-dimethoxyphenol (canolol) isolated from canola oH. Journal of Agricultural and Food Chemistry, 52 4380-4387 (2004). 

More recently, another derivative of sinapic acid has been identified because of its highly potent antioxidant activity and the antimutagenic and anticarcino-genic properties (Kuwahara et al., 2004 Vuorela et al., 2005 Cao et al., 2008). This derivative, 2,6-dimethoxy-4-vinylphenol (vinylsyringol) or canolol, was first identified in two independent studies by Koski et al. (2003) and Wakamatsu et al. (2005) in crude canola oil. Kuwahara et al. (2004) described the antimutagenic potency of this compound as higher than a-tocopherol, P-carotene, vitamin C... 

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